Geneexpression and in vitro function of mesenchymal stromal
- Slides: 6
Gene-expression and in vitro function of mesenchymal stromal cells are affected in juvenile myelomonocytic leukemia by Friso G. J. Calkoen, Carly Vervat, Else Eising, Lisanne S. Vijfhuizen, Peter-Bram A. C. ‘t Hoen, Marry M. van den Heuvel-Eibrink, R. Maarten Egeler, Maarten J. D. van Tol, and Lynne M. Ball haematol Volume 100(11): 1434 -1441 October 31, 2015 © 2015 by Ferrata Storti Foundation
Patients’ characteristics. Friso G. J. Calkoen et al. Haematologica 2015; 100: 1434 -1441 © 2015 by Ferrata Storti Foundation
Expansion and characterization of mesenchymal stromal cells (MSC) from juvenile myelomonocytic leukemia (JMML) patients at diagnosis and post-hematopoietic stem cell transplantation (HSCT) and healthy controls. Friso G. J. Calkoen et al. Haematologica 2015; 100: 1434 -1441 © 2015 by Ferrata Storti Foundation
Juvenile myelomonocytic leukemia mesenchymal stromal cells (JMML-MSC) support the proliferation and differentiation of HPCs in vitro. Friso G. J. Calkoen et al. Haematologica 2015; 100: 1434 -1441 © 2015 by Ferrata Storti Foundation
Gene expression of differentially expressed genes in mesenchymal stromal cells of juvenile myelomonyctic leukemic (MSC-JMML) patients at time of diagnosis and after hematopoietic stem cell transplantation (HSCT). Friso G. J. Calkoen et al. Haematologica 2015; 100: 1434 -1441 © 2015 by Ferrata Storti Foundation
Mesenchymal stromal cells of juvenile myelomonyctic leukemic (JMML-MSCs) expanded from bone marrow at diagnosis have an increased suppressive effect on monocyte to immature dendritic cell differentiation but not on NK-cell activation. Friso G. J. Calkoen et al. Haematologica 2015; 100: 1434 -1441 © 2015 by Ferrata Storti Foundation