Gene Therapy GCSE Module 14 Lesson 10 b

Gene Therapy GCSE Module 14 Lesson 10 b Gene therapy and the ethical issues it raises

Lesson objectives: • You will understand what gene therapy hopes to achieve and the two main types. • You will understand the role vectors have in transferring the genetic material and the different types used. • You will appreciate the ethical implications of gene therapy and the moral dilemma raised by the recent case of Charlie Whitaker.

Activities: Gene therapy is defined as the insertion of health genes into body cells to replace disease causing alleles. There are two types of gene therapy. Read the information on the two types and how they could be used to treat inherited disorders in the future. Gene Therapy. doc Then the article and links from the BBC on the recent case of Charlie Whitaker. BBC NEWS | Health | Designer baby transplant success

Copy the questions below and answer: 1. What does gene therapy aim to do? 2. Explain clearly the difference between the two types of gene therapy? 3. What conditions must be fulfilled for gene therapy to be successful? 4. Explain in detail the difference between each vector? 5. Read clearly the ethical considerations in gene therapy section and then discuss whether you feel, “gene therapy is playing God”.

Plenary: Take 15 minutes with a partner to discuss the issues raised by the questions and then decide whether you are for or against gene therapy being used and in what circumstances it may be acceptable – if at all! Prepare some notes on your thoughts to use later in the class discussion. Put forward your views during the class discussion but always remember to allow others to speak and voice their opinions – even if you disagree.