Gene Regulation by Dr Ulhas Patil Department of
Gene Regulation by Dr. Ulhas Patil Department of Microbiology and Biotechnology R. C. Patel A. S. C. College, SHIRPUR – 425 405 Phone (02563) 257328 (offi. ) (02563) 259034 (Resi. ) Mobile - 9422260313 E-mail – ulhaskpatil@gmail. com Lecture is prepared for learning presentation skill during FDP 101 X IITB
18 December 2021 Whether bacteria are Intelligent ? Glucose Lactose Which sugar will be utilized by bacteria? 2
Basic you must know Central Dogma of Molecular biology 18 December 2021 3
Types of gene • Bacterial genomes contain several thousand different genes • Those genes which are required by the cell under all growth conditions and are called housekeeping/constitutive gene e. g. DNA polymerase, RNA polymerase • Many other gene products are required under specific growth conditions and are called inducive gene. e. g. gene requires for enzymes to split specific sugars, 18 December 2021 4
Modes of gene regulation Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene. regulation. It can occur at three possible places in the production of an active gene product. Transcriptional regulation : transcription of the gene can be regulated. Translational regulation : after synthesis of m. RNA, translation process is regulated 18 December 2021 Post-transcriptional / post-translational: after completely synthesis of protein 5
Induction and repression Induction: A substance which induced the synthesis of enzyme/protein is called inducer and process is called induction. Repression: A substance which represses the synthesis of enzyme/protein is called repressor and process is called repressor. 18 December 2021 6
Thank You Please suggest me improvements at ulhaskpatil@gmail. com 18 December 2021 7
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