GENE Gene editing 15211010029 15211010031 15211010016 Gene editingcrispr

GENE Gene editing 曾嘉乐 15211010029 黄金莲 15211010031 丁赞全 15211010016

Gene editing―crispr It’s an advance in gene editing which can offer cures and treatments for some of deadly diseases. We can find new ways to treat genetic disease， infectious disease and cancer.

CRISPR, a revolutionary gene editing technology that enables efficient and precise genomic modifications（修改） in a wide variety of organisms （生物） and tissues.

Words in the video • • • biomedical laboratory 生物医学实验室 trigger 引发 molecular scissors 分子剪刀 type Ⅰ diabetes Ⅰ型糖尿病 pancreas 胰腺 Insulin 胰岛素 stealth 隐藏 Islets 胰岛 kidney failure or cardiovascular disease 肾衰竭和心血管疾 病 envisage 设想

GENE A. B. C. What is the CRISPR gene editing？ The immunologist how to make the human immune system won’t reject the transplant. The secondary complications（并发症） of Type 1 diabetes are？

GENE A. B. CRISPR gene editing enables scientists to scan the entire genome, and using molecular scissors to cut both strands of DNA and delete, insert or repair the code. They would delete some key genetic markers that identify the pig cells as foreign. (make it more human-like) damage their nerves, impair their vision, cause kidney failure or cardiovascular disease

• • Mitochondria Organism Heredity Allele Nucleic acid Organelles Genetically Genetic make up 线粒体 有机体 遗传性 等位基因 核酸 细胞器 遗传学角度 基因组合

Find his parents

What are genes • A gene is a unit of DNA that is usually located on a chromosome and that controls the development of one or more traits and is the basic unit by which genetic information is passed from parent to offspring • Biologically, it is a part of a cell that controls or influences the appearance, growth, etc. of a living thing F: 什么是基因 - What is a gene (Stated. Clearly)_高清. mp 4

Structure • The most common form of DNA in a cell is in a double helix structure, in which two individual DNA strands twist aro und each other in a right-handed spiral. In this structure, the base pairing rul es specify that guanine pairs with cytosine and adenine pairs with thymine.

• Gene hold the information to build and mai ntain an organism’s cells and pass genetic traits to offspring, although some organell es (e. g. mitochondria) are self-replicating and are not coded for by the organism’s DNA.

• Colloquial usage of term “gene”(e. g. good gene, hair color gene) may be actually refer to an allele: a gene is the basic instruction, a sequence of nucleic acid (DNA or, in the case of certain viruses RNA), while an allele is one variant of that gene.

QUICK ANSWER • A genetic characteristic of an individual is any trait that can be attributed to a hereditary cause, coded for in inherited DNA. Any other trait is derived from environmental causes, either while within the womb or outside of it. It can be very difficult to determine if a characteristic is genetic, congenital but not genetic or acquired after birth • Among the genes that cause various characteristics in individuals, some are dominant and some are recessive

• Generally, any characteristic that appears in one family for several generations is suspected to have a genetic cause. Some genetic characteristics are fairly well-known and uncontroversial. These include such benign traits as hair color, eye color, attachment of earlobes, hair texture and freckles. However, just because a trait has a genetic basis does not mean that a person with that gene will have that characteristic

Gene editing • Regularly Interspaced short Palindromic Repeats规律间隔的短回文重复序列

• Wide application Laboratories around the world have adopted this technology in animals, plants, humans, fungother bacteria essentially any kind of organism that labs are studying.

• It provides the opportunity to cure genetic disease, infected diseases and cancer in the future. • In late 80 s, gene editing first supply to 80 HIV patients, and HIV is basically become a stable, chronic, massageable illness. • The next gene editing trail will be in patients with the serious blood clotting disorder hemophilia.