Future trends RD Implementing Enabling technologies Semantic webs

Future trends- R&D · Implementing Enabling technologies - Semantic webs : eg Bio. DASH, - Robot scientists · Inherent Beurocracy - Phase focused specialised CROs · Complex & large trials help understand population responses not individualise it - Use of Biomarkers · Use of “pervasive healthcare” - Use of robust portable monitoring devices 1

Future trends- Supply Chain · Growing Globalisation & complexity · “Assembled to order” rather than “made to forecast” · Outsourcing not to save costs only but leverage expertise · Reduce traditional distribution chains to dispensers of specialised service packages · Automated dispensing of primary care & direct delivery of specilised medicines – freeing the time of pharmacist for more specialised services · Use of DNA labelling & smart dust to track a medcine – anytime anywhere 2

Future trends · M&A - Increase investment - Gain technology expertise eg Roche & Genentech · Virtualisation : Strategic outsourcing · Pharmacogenomics: personalised therapeutics of the future · Diversification - Genetic Diagnostics : packages offering innovative therapeutics and diagnostic kits to target correct patient population • eg Herceptin & Hercep Test ( Genen. Tech): Helps Detect the 25 -30% persons who over express the HER 2 protein & thus give 100% results in those treated- charge a price premium - HIT based databases to lead towards desired “value product” · Regulatory consolidation · Supply chain Shift focus from production of pharmaceuticals alone to large Integrated healthcare companies providing value added product offerings 3