FUNDAMENTAL MICROBIOLOGY INTRODUCTION John Sippel Ph D FUNDAMENTAL

FUNDAMENTAL MICROBIOLOGY INTRODUCTION John Sippel, Ph. D.

FUNDAMENTAL MICROBIOLOGY SYLLABUS • • • Course Meetings Course Description Texts Course Learning Outcomes General Class Policies General Lab Policies Dates Grading Missed Exams Academic Integrity

FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE • • Immunology Microbiology Infectious Disease Microbial Diseases by Systems

FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE • Immunology – Elements of the immune response • Cells of the Immune System • Cytokines, Chemokines, Complement, Eicosanoids • Apoptosis, Acute Phase Response • Inflammation, Fever – Innate Immunity • 1 st Line = Barriers: mechanical, chemical • 2 nd Line = inflam, complement, phagocytosis, interferon – Adaptive Immunity • Humoral = antibody • Cell Mediated = cytotoxic T cells, activated Macs

FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE Microbiology Bacteriology structure, physiology Gram pos, Gram neg, Mycobacteria, Spirochetes Virology structure / replication; icosohedral / helical RNA / DNA; nominclature Mycology yeasts / molds dermatophytes, subcutaneous, systemic, opportunist Parasitology protozoa: amoeba, sporozoa, flagellates helminths: nematodes, trematodes, cestodeds

FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE • Infectious Diseases – Epidemiology; reservoirs • Emerging infectious diseases • Bioterrorism – Route of entry – Pathogenesis – Host response – Diagnosis – Management • Antibiotics – Prevention • Chemoprophylaxis • immunoprophylaxis

FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE • Microbial Diseases by Systems – – – – Respiratory Digestive Genitourinary Central Nervous System (CNS) Blood Skin, eyes HIV and AIDS