Frederickson Classification of Hyperlipoproteinemia Phenotype I IIa IIb
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고지혈증의 분류: Frederickson Classification of Hyperlipoproteinemia Phenotype I IIa IIb III IV V Lipoprotein CM LDL/VLDL CM/VLDL Triglyceride ++++ - ++ ++ to +++ ++ ++++ Cholesterol + to ++ ++ to +++ - to + ++ to ++++ Plasma Lactescent Clear Turbid Lactescent Xanthomas Eruptive Tendon, tuberous None Palmar, tuberoerupti ve None Eruptive CAOD - +++ +++ +/- Pancreatitis +++ 0 0 +++ Mol. Defects LPL, apo. CII LDL-R, Apo- Unknown B 100, PCSK 9, LDLRAP, ABCG 5/8 Apo. E Apo. A-V, GPIHBP 1 Diseases FH, FDBL FHTG FHTC FCS FCHL
고지혈증의 진단 공복시 혈액 검사: • Total Cholesterol • Triglyceride • HDL-cholesterol • LDL-cholesterol (직접 측정, 혹은 계산: LDL = Total – HDL – TG/5) 16
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