FOSBAC PLUS T FT IN BROILER PRODUCTION Technical

FOSBAC PLUS T (F+T) IN BROILER PRODUCTION Technical Department Bedson Africa

WHAT IS F+T • It is a broad spectrum antibiotic effective against gram positive and gram negative bacteria like E. coli, Samonella, Pasteurella, etc. and Mycoplasma.

MAIN INGREDIENTS • • Fructose 1. 6 Diphosphate 18% Fosfomycin 20% Tylosin 5% (pure) Electrolytes

FRUCTOSE 1. 6 DIPHOSPHATE 18% 1. As auxiliary Energy Source that helps animals to recuperate from disease, helping them to continue eating while recuperating. 2. To ”camouflage” Fosfomycin to the bacteria membrane wall receptors and completely eliminate bacterial resistance. 3. It acts as a Vehicle in transport of the active ingredients allowing the antibiotic to enter the bacteria cell and reach the target area quicker.

FOSFOMYCIN 20% • Broad spectrum antibiotic. • Smallest antibiotic molecule, reaching areas like bone and abscesses. • Does not bind to proteins, so it is freely available. • Non-toxic.

TYLOSIN 5% (PURE) • Effective against Mycoplasmas • Synergistic effect with Fosfomycin improving therapeutic effect of product • Dose of active ingredient per kg of body weight is effective enough in F + T.

ELECTROLYTES • Immediate re-hydration • Re-hydration of day old chicks when arriving from hatchery due to changes in humidity from hatchery to farm. • Help the sick bird to recover from imbalances due to fever or diarrhea

WHY IS F+T A SUPERIOR PRODUCT 1. 2. 3. 4. 5. 6. 7. Effective against a wide range of bacteria. Reliable/trustworthy - permanently active, NO RESISTANCE! Efficient – The smallest molecule – fast absorption, fast elimination Versatile – Available in water soluble powder and premix forms Safe - No possibility of overdosing – literally non toxic Flexible – Dose can be used at different levels for variety of problems. Resourceful – energizing compound accelerate the processes of recovery

BENEFITS OF F+T • Suppresses bacterial growth • Improves production parametres • Improved gain first 7 days, carries over at the end of the cycle. • Improve live body weight at the end of the cycle. • Improved FCR • Less or minimum mortality • Other benefits

TARGETS OF BROILER PRODUCTION • Live Body Weight (LBW) • Feed Conversion Rate (FCR) • Minimum mortality

F+T PROGRAM FOR PREVENTION OF SECONDARY BACTERIAL INFECTIONS IN BROILERS F+T premix – for ± 15 days eliminates “Hot spot” in broilers. F+T w/s - first 5 days “Clean out” Week No. 1 2 3 4 5 6

F+T PROGRAM APPLICATIONS 1. 2. 3. Water soluble - first 5 days of broiler’s life in drinking water - “Clean out” / Energy booster 160 mg (0. 16 gr. ) / kg Live body weight / day Premix – preventative treatment of “Hot spot” day 20 -35 500 - 800 gr. / Ton of feed (48 mg / kg Lbw) Treatment - in drinking water 160 mg (0. 16 gr. ) / kg Live body weight / day

1. FIRST 5 DAYS OF LIFE (water soluble presentation)

DOSAGE CALCULATION FIRST FIVE DAYS - IN WATER PER DAY: Kg. LIVE BODY WEIGHT AT THE LAST DAY OF THERAPY X 160 mg. F+T In practice 160 g of F+T is required for the treatment of 1000 kg/LBW

BENEFITS FIRST 5 DAYS OF LIFE • Clean out effect: eliminates the main incidence of infections in the one day old baby chick. • Provide easy to absorb energy and electrolytes for re-hydration when arriving from hatchery • Improves weights at 7 days.

2. PREVENTATIVE TREATMENT (premix presentation)

DOSAGE CALCULATION PREVENTION - IN FEED PER TON: Kg. LIVE BODY WEIGHT AT THE LAST DAY OF THERAPY X 48 mg. F+T ESTIMATED FEED CONSUMPTION IN Kg AT THE LAST DAY OF THERAPY

BENEFITS OF PREVENTATIVE TREATMENT • • 1 -2 days feed savings (Huge economic impact) FCR (Financial benefits) Weight gain (Financial benefits) Reduction in mortality Electricity cost savings Labor cost savings More open days for cleaning and biosecurity

3. TREATMENT (water soluble presentation)

DOSAGE CALCULATION TREATMENT - IN WATER PER DAY Kg. LIVE BODY WEIGHT AT THE LAST DAY OF THERAPY X 160 mg. F+T * TREATMENT PERIOD 3 -5 DAYS *In practice 160 g of F+T is required for the treatment of 1000 kg/LBW

BENEFITS OF TREATMENT • Immediate reduction in mortality • Compatibility with other antibiotics • Effective against E. coli, Salmonella, Pasteurella, Staphylococcus, Pseudomonas, etc. • Energy and electrolytes will help the bird on the recovery process.

E. coli SUSCEPTIBILITY TO ANTIBIOTICS ACTIVE INGREDIENT 1992 1993 1994 1995 1996 1997 1998 TETRACYCLINE 27 22 20 9 10 7 5 CLORAMPHENICOL 92 85 83 79 80 77 79 AMPICILLIN 60 54 44 41 43 40 39 STREPTOMYCIN 14 18 10 26 15 20 17 SULFA + TRIM 69 71 64 68 67 67 64 NORFLOXACIN 98 92 80 77 79 76 67 99. 7 85 70 65 56 48 47 99 98 98 98 96 97 96 ENROFLOXACIN FOSFOMYCIN Fosbac + T has been constantly effective throughout the years!

SUMMARY • Fosbac plus T reduces costs, by improving production parameters (feed conversion, weight, mortality and uniformity). • Reduces secondary bacterial problems E. coli/PPLO (caused by primary viral infections). • Prevents bacterial intestinal infections Salmonella.

SUMMARY (cont) • Improves uniformity of the flock (mixing of product in feed is critical). • Prevents losses due to illness during critical periods (natural and stress-induced immunosuppression). • Lowers the mortality rate of birds at the end of the growth cycle. • Reduces post vaccinal reactions.