For Healthcare professional only The CARTO 3 System

For Healthcare professional only

The CARTO® 3 System It’s not just a software upgrade …. . Hardware/Software • New PIU/work station • New graphic user interface • 1 Million lines of new software code Catheters/Patches • NAVISTAR® Tx Catheters • EZ STEER™ THERMOCOOL® • CARTO® 3 System Dx with EEPROM technology • New patch system Workflow • CONNECTION OF CHOICE™

Key Features & Benefits CARTO® System Technology Enhancements Advanced Catheter Location (ACL) Fast Anatomical Mapping (FAM) CONNECTION OF CHOICE™ Accurate visualization of catheters Speed Superior Workflow

Advanced Catheter Location (ACL) ACL= Accuracy Electromagnetic mapping • Electromagnetic mapping (EM) – CARTO® System Sensor registers current ratio to point in space (electromagnetic mapping) • Current based mapping – Each electrode emits low current signal on unique frequency – Signal detected by 6 patches, current ratio created + Visualisation Current based mapping

ACL: Matrix Creation Matrix = Registration of EM locations and current ratios • As sensor-catheter moves about chamber, matrix of locations with associated current ratios is created • With matrix, all catheters can be visualized • No distortions related to impedance changes : With sensor-catheter, matrix is updated as patient impedance changes

Ablating around LASSO® Catheter

LASSO® Catheter Click and See

ACL: Multi-Catheter Visualization • Realistic visualization • Visualize up to 5 catheters simultaneously • All electrodes can be seen (tip and curve) • Linear space is maintained (scale is not distorted within space)

ACL: Features and Expected Benefits ACL Features ACL Benefits LASSO® Catheter. Visualization Reduced Fluoroscopy, Ease of Use Multi Catheter visualisation Reduced Fluoroscopy, Spatial Orientation LASSO® Catheter Click-’n-See Reduced procedure time, Ease of Use, Clinical Precision Matrix No Impedance distortions gives Realistic visualisation Quality

Key Features & Benefits CARTO® System Technology Enhancements (ACL) Accurate visualisation of all catheters Fast Anatomical Mapping Speed Advanced Catheter Location (FAM) CONNECTION OF CHOICE™ Superior Workflow

Fast Anatomical Mapping (FAM) • Using NAVISTAR ® Catheter Accurate • All electrodes utilized to create the map Fast • Reconstruction algorithm for CT-like anatomy Realistic • Collection of electroanatomical during FAM map points Fast • No dynamic registration Realistic

FAM–Technology

FAM: Features and Expected Benefits Fast Anatomical Mapping FAM Benefits 60 points/second Acquisition Rate Rapid Volume Creation Reconstruction algorithm Realistic Maps, easy to navigate Regional Resolution Efficiency, Safety Multi Structure Mapping Clear orientation Quality

Key Features & Benefits CARTO® System. Technology Enhancements Advanced Catheter Location (ACL) Fast Anatomical Mapping (FAM) CONNECTION OF CHOICE™ Accurate visualisation of all catheters Speed Superior Workflow

CONNECTION OF CHOICE • All catheters can connect through the PIU • Single setup for every type of case. Navigation or not • No tip- pins for Biosense Webster catheters • Simple, error-free connections • Reduced setup time for staff • Reduced stress • ™ Easy patch placement • Easy access to NAV • Just open a NAVISTAR® catheter

CONNECTION OF CHOICE™ Benefits Single Setup Reduced setup time, Ease of Use Easy patch placement Easy Access To NAV, More clinical options Potential reduction of Procedure Cost Possibility to open up for more types of procedures Open Catheter Choice Support variety of clinical approaches Simple Connection Reduce procedure time, Ease of Use

Key Features & Benefits CARTO® System Technology Enhancements Advanced Catheter Location (ACL) Fast Anatomical Mapping (FAM) CONNECTION OF CHOICE™ Accurate visualisation of all catheters Speed Superior Workflow

You get more… • High Quality Signals More detail- More precision • Enlarged mapping area Efficiency • Improved ref patch system – Designed to be less sensitive to patient movement Efficiency

With CARTO 3 you have been able to visualize 3 D electroanatomical maps of your patients hearts. This year , you will be able to “ touch “ it. Thank You