Focus on Shock Relates to Chapter 67 Nursing

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Focus on Shock (Relates to Chapter 67, “Nursing Management: Shock, SIRS, and Multiple Organ

Focus on Shock (Relates to Chapter 67, “Nursing Management: Shock, SIRS, and Multiple Organ Dysfunction Syndrome, ” in the textbook) Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Shock § Syndrome characterized by decreased tissue perfusion and impaired cellular metabolism n Imbalance

Shock § Syndrome characterized by decreased tissue perfusion and impaired cellular metabolism n Imbalance in supply/demand for O 2 and nutrients Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Shock (Cont’d) § Classification of shock (table 67 -1) n Low blood flow Cardiogenic

Shock (Cont’d) § Classification of shock (table 67 -1) n Low blood flow Cardiogenic n Hypovolemic n n Maldistribution of blood flow Septic n Anaphylactic n Neurogenic n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Low Blood Flow Cardiogenic Shock § Definition n Systolic or diastolic dysfunction leads to

Low Blood Flow Cardiogenic Shock § Definition n Systolic or diastolic dysfunction leads to compromised cardiac output Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Low Blood Flow Cardiogenic Shock (Cont’d) § Precipitating causes n Myocardial infarction n Cardiomyopathy

Low Blood Flow Cardiogenic Shock (Cont’d) § Precipitating causes n Myocardial infarction n Cardiomyopathy n Blunt cardiac injury n Severe systemic or pulmonary hypertension n Cardiac tamponade n Myocardial depression from metabolic problems Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Pathophysiology of Cardiogenic Shock Fig. 67 -2 Copyright © 2010, 2007, 2004, 2000, Mosby,

Pathophysiology of Cardiogenic Shock Fig. 67 -2 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Low Blood Flow Cardiogenic Shock § Early manifestations n Tachycardia n Hypotension n Narrowed

Low Blood Flow Cardiogenic Shock § Early manifestations n Tachycardia n Hypotension n Narrowed pulse pressure n ↑ Myocardial O 2 consumption Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Low Blood Flow Cardiogenic Shock (Cont’d) § Physical examination n Tachypnea, pulmonary congestion n

Low Blood Flow Cardiogenic Shock (Cont’d) § Physical examination n Tachypnea, pulmonary congestion n Pallor; cool, clammy skin n Decreased capillary refill time n Anxiety, confusion, agitation § ↑ in pulmonary artery wedge pressure § Decreased renal perfusion and UO Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Low Blood Flow Hypovolemic Shock § Absolute hypovolemia: Loss of intravascular fluid volume n

Low Blood Flow Hypovolemic Shock § Absolute hypovolemia: Loss of intravascular fluid volume n Hemorrhage n GI loss (e. g. , vomiting, diarrhea) n Fistula drainage n Diabetes insipidus n Hyperglycemia n Diuresis Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Low Blood Flow Hypovolemic Shock (Cont’d) § Relative hypovolemia n Results when fluid volume

Low Blood Flow Hypovolemic Shock (Cont’d) § Relative hypovolemia n Results when fluid volume moves out of the vascular space into extravascular space (e. g. , interstitial or intracavitary space) n Termed third spacing Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Pathophysiology of Hypovolemic Shock Fig. 67 -3 Copyright © 2010, 2007, 2004, 2000, Mosby,

Pathophysiology of Hypovolemic Shock Fig. 67 -3 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Low Blood Flow Hypovolemic Shock (Cont’d) § Clinical manifestations n Anxiety n Tachypnea n

Low Blood Flow Hypovolemic Shock (Cont’d) § Clinical manifestations n Anxiety n Tachypnea n Increase in CO, heart rate n Decrease in stroke volume, PAWP, UO § If loss is >30%, blood volume is replaced Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Neurogenic Shock § Hemodynamic phenomenon that can occur within 30

Maldistribution of Blood Flow Neurogenic Shock § Hemodynamic phenomenon that can occur within 30 minutes of a spinal cord injury at the fifth thoracic (T 5) vertebra or above and can last up to 6 weeks Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Neurogenic Shock (Cont’d) § Can be in response to spinal

Maldistribution of Blood Flow Neurogenic Shock (Cont’d) § Can be in response to spinal anesthesia § Results in massive vasodilation leading to pooling of blood in vessels n Compensation is lost due to the loss of SNS vasoconstrictor tone Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Pathophysiology of Neurogenic Shock Fig. 67 -4 Copyright © 2010, 2007, 2004, 2000, Mosby,

Pathophysiology of Neurogenic Shock Fig. 67 -4 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Neurogenic Shock (Cont’d) § Clinical manifestations n Hypotension n Bradycardia

Maldistribution of Blood Flow Neurogenic Shock (Cont’d) § Clinical manifestations n Hypotension n Bradycardia n Temperature dysregulation (resulting in heat loss) n Dry skin n Poikilothermia (taking on the temperature of the environment) Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Anaphylactic Shock § Acute, life-threatening hypersensitivity reaction n Massive vasodilation

Maldistribution of Blood Flow Anaphylactic Shock § Acute, life-threatening hypersensitivity reaction n Massive vasodilation n Release of inflammatory mediators n ↑ Capillary permeability Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Anaphylactic Shock (Cont’d) § Clinical manifestations n Swelling of the

Maldistribution of Blood Flow Anaphylactic Shock (Cont’d) § Clinical manifestations n Swelling of the lips and tongue, angioedema n Wheezing, stridor n Flushing, pruritus, urticaria n Respiratory distress and circulatory failure Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Anaphylactic Shock (Cont’d) § Clinical manifestations n Anxiety, confusion, dizziness

Maldistribution of Blood Flow Anaphylactic Shock (Cont’d) § Clinical manifestations n Anxiety, confusion, dizziness n Sense of impending doom n Chest pain n Incontinence Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Septic Shock § Sepsis: Systemic inflammatory response to documented or

Maldistribution of Blood Flow Septic Shock § Sepsis: Systemic inflammatory response to documented or suspected infection § Severe sepsis = Sepsis + Organ dysfunction Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Septic Shock (Cont’d) § Septic shock = Presence of sepsis

Maldistribution of Blood Flow Septic Shock (Cont’d) § Septic shock = Presence of sepsis with hypotension despite fluid resuscitation + Presence of tissue perfusion abnormalities Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Septic Shock (Cont’d) § Mortality rates as high as 50%

Maldistribution of Blood Flow Septic Shock (Cont’d) § Mortality rates as high as 50% § Primary causative organisms n Gram-negative and gram-positive bacteria n Endotoxin stimulates inflammatory response Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Pathophysiology of Septic Shock Fig. 67 -5 Copyright © 2010, 2007, 2004, 2000, Mosby,

Pathophysiology of Septic Shock Fig. 67 -5 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Septic Shock § Clinical manifestations n ↑ Coagulation and inflammation

Maldistribution of Blood Flow Septic Shock § Clinical manifestations n ↑ Coagulation and inflammation n ↓ Fibrinolysis Formation of microthrombi n Obstruction of microvasculature n n Hyperdynamic state: Increased CO and decreased SVR Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Maldistribution of Blood Flow Septic Shock (Cont’d) § Clinical manifestations n Tachypnea/hyperventilation n Temperature

Maldistribution of Blood Flow Septic Shock (Cont’d) § Clinical manifestations n Tachypnea/hyperventilation n Temperature dysregulation n ↓ Urine output n Altered neurologic status n GI dysfunction n Respiratory failure is common Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Initial Stage § Usually not clinically apparent § Metabolism changes from

Stages of Shock Initial Stage § Usually not clinically apparent § Metabolism changes from aerobic to anaerobic n Lactic acid accumulates and must be removed by blood and broken down by liver n Process requires unavailable O 2 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Compensatory Stage § Clinically apparent n Neural n Hormonal n Biochemical

Stages of Shock Compensatory Stage § Clinically apparent n Neural n Hormonal n Biochemical compensatory mechanisms § Attempts are aimed at overcoming consequences of anaerobic metabolism and maintaining homeostasis Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Compensatory Stage of Shock Fig. 67 -6 Copyright © 2010, 2007, 2004, 2000, Mosby,

Compensatory Stage of Shock Fig. 67 -6 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Compensatory Stage § Baroreceptors in carotid and aortic bodies activate SNS

Stages of Shock Compensatory Stage § Baroreceptors in carotid and aortic bodies activate SNS in response to ↓ BP n Vasoconstriction while blood to vital organs maintained § ↓ Blood to kidneys activates renin– angiotensin system n ↑ Venous return to heart, CO, BP Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Compensatory Stage (Cont’d) § Impaired GI motility n Risk for paralytic

Stages of Shock Compensatory Stage (Cont’d) § Impaired GI motility n Risk for paralytic ileus § Cool, clammy skin from blood n Except septic patient who is warm and flushed Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Compensatory Stage (Cont’d) § Shunting blood from lungs increases physiologic dead

Stages of Shock Compensatory Stage (Cont’d) § Shunting blood from lungs increases physiologic dead space ↓ Arterial O 2 levels n Increase in rate/depth of respirations n V/Q mismatch n § SNS stimulation increases myocardium O 2 demands Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Compensatory Stage (Cont’d) § If perfusion deficit corrected, patient recovers with

Stages of Shock Compensatory Stage (Cont’d) § If perfusion deficit corrected, patient recovers with no residual sequelae § If deficit not corrected, patient enters progressive stage Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage § Begins when compensatory mechanisms fail § Aggressive interventions

Stages of Shock Progressive Stage § Begins when compensatory mechanisms fail § Aggressive interventions to prevent multiple organ dysfunction syndrome Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Progressive Stage of Shock Fig. 67 -7 Copyright © 2010, 2007, 2004, 2000, Mosby,

Progressive Stage of Shock Fig. 67 -7 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § Hallmarks of ↓ cellular perfusion and altered

Stages of Shock Progressive Stage (Cont’d) § Hallmarks of ↓ cellular perfusion and altered capillary permeability: Leakage of protein into interstitial space n ↑ Systemic interstitial edema n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § Movement of fluid from pulmonary vasculature to

Stages of Shock Progressive Stage (Cont’d) § Movement of fluid from pulmonary vasculature to interstitium Pulmonary edema n Bronchoconstriction n ↓ Residual capacity n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § Fluid moves into alveoli Edema n Decreased

Stages of Shock Progressive Stage (Cont’d) § Fluid moves into alveoli Edema n Decreased surfactant n Worsening V/Q mismatch n Tachypnea n Crackles n Increased work of breathing n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § CO begins to fall Decreased peripheral perfusion

Stages of Shock Progressive Stage (Cont’d) § CO begins to fall Decreased peripheral perfusion n Hypotension n Weak peripheral pulses n Ischemia of distal extremities n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § Myocardial dysfunction results in Dysrhythmias n Ischemia

Stages of Shock Progressive Stage (Cont’d) § Myocardial dysfunction results in Dysrhythmias n Ischemia n Myocardial infarction n End result: Complete deterioration of cardiovascular system n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § Mucosal barrier of GI system becomes ischemic

Stages of Shock Progressive Stage (Cont’d) § Mucosal barrier of GI system becomes ischemic Ulcers n Bleeding n Risk of translocation of bacteria n Decreased ability to absorb nutrients n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § Liver fails to metabolize drugs and wastes

Stages of Shock Progressive Stage (Cont’d) § Liver fails to metabolize drugs and wastes Jaundice n Elevated enzymes n Loss of immune function n Risk for DIC and significant bleeding n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Progressive Stage (Cont’d) § Acute tubular necrosis/acute renal failure Copyright ©

Stages of Shock Progressive Stage (Cont’d) § Acute tubular necrosis/acute renal failure Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Refractory Stage § Exacerbation of anaerobic metabolism § Accumulation of lactic

Stages of Shock Refractory Stage § Exacerbation of anaerobic metabolism § Accumulation of lactic acid § ↑ Capillary permeability Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Refractory Stage of Shock Fig. 67 -8

Refractory Stage of Shock Fig. 67 -8

Stages of Shock Refractory Stage § Profound hypotension and hypoxemia § Tachycardia worsens §

Stages of Shock Refractory Stage § Profound hypotension and hypoxemia § Tachycardia worsens § Decreased coronary blood flow § Cerebral ischemia Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Stages of Shock Refractory Stage (Cont’d) § Failure of one organ system affects others

Stages of Shock Refractory Stage (Cont’d) § Failure of one organ system affects others § Recovery unlikely Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Diagnostic Studies § Thorough history and physical examination § No single study to determine

Diagnostic Studies § Thorough history and physical examination § No single study to determine shock n Blood studies Elevation of lactate n Base deficit n n 12 -lead ECG n Chest x-ray n Hemodynamic monitoring Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care § Successful management includes n Identification of patients at risk for shock

Collaborative Care § Successful management includes n Identification of patients at risk for shock n Integration of the patient’s history, physical examination, and clinical findings to establish a diagnosis Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § Successful management includes n Interventions to control or eliminate the

Collaborative Care (Cont’d) § Successful management includes n Interventions to control or eliminate the cause of the decreased perfusion n Protection of target and distal organs from dysfunction n Provision of multisystem supportive care Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § General management strategies n Ensure patent airway n Maximize oxygen

Collaborative Care (Cont’d) § General management strategies n Ensure patent airway n Maximize oxygen delivery Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § Cornerstone of therapy for septic, hypovolemic, and anaphylactic shock =

Collaborative Care (Cont’d) § Cornerstone of therapy for septic, hypovolemic, and anaphylactic shock = volume expansion n Isotonic crystalloids (e. g. , normal saline) for initial resuscitation of shock Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § Volume expansion n If the patient does not respond to

Collaborative Care (Cont’d) § Volume expansion n If the patient does not respond to 2 to 3 L of crystalloids, blood administration and central venous monitoring may be instituted n Complications of fluid resuscitation § Hypothermia § Coagulopathy Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § Primary goal of drug therapy = correction of decreased tissue

Collaborative Care (Cont’d) § Primary goal of drug therapy = correction of decreased tissue perfusion n Vasopressor drugs (e. g. , epinephrine, dopamine) Achieve/maintain MAP >60 to 65 mm Hg n Reserved for patients unresponsive to otherapies n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § Primary goal of drug therapy = correction of decreased tissue

Collaborative Care (Cont’d) § Primary goal of drug therapy = correction of decreased tissue perfusion n Vasodilator therapy (e. g. , nitroglycerin [cardiogenic shock], n Achieve/maintain MAP >60 to 65 mm Hg Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § Nutrition is vital to decreasing morbidity from shock n Initiate

Collaborative Care (Cont’d) § Nutrition is vital to decreasing morbidity from shock n Initiate enteral nutrition within the first 24 hours Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care (Cont’d) § Nutrition is vital to decreasing morbidity from shock n Initiate

Collaborative Care (Cont’d) § Nutrition is vital to decreasing morbidity from shock n Initiate parenteral nutrition if enteral feedings contraindicated or fail to meet at least 80% of the caloric requirements n Monitor protein, nitrogen balance, BUN, glucose, electrolytes Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Cardiogenic Shock § Restore blood flow to the myocardium by restoring the balance

Collaborative Cardiogenic Shock § Restore blood flow to the myocardium by restoring the balance between O 2 supply and demand § Thrombolytic therapy § Angioplasty with stenting § Emergency revascularization § Valve replacement Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Cardiogenic Shock (Cont’d) § Hemodynamic monitoring § Drug therapy (e. g. , diuretics

Collaborative Cardiogenic Shock (Cont’d) § Hemodynamic monitoring § Drug therapy (e. g. , diuretics to reduce preload) § Circulatory assist devices (e. g. , intraaortic balloon pump, ventricular assist device) Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Hypovolemic Shock § Management focuses on stopping the loss of fluid and

Collaborative Care Hypovolemic Shock § Management focuses on stopping the loss of fluid and restoring the circulating volume § Fluid replacement Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Septic Shock § Fluid replacement (e. g. , 6 to 10 L

Collaborative Care Septic Shock § Fluid replacement (e. g. , 6 to 10 L of isotonic crystalloids and 2 to 4 L of colloids) to restore perfusion n Hemodynamic monitoring § Vasopressor drug therapy if unresponsive to fluids Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Septic Shock (Cont’d) § Intravenous corticosteroids for patients who require vasopressor therapy,

Collaborative Care Septic Shock (Cont’d) § Intravenous corticosteroids for patients who require vasopressor therapy, despite fluid resuscitation, to maintain adequate BP Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Septic Shock (Cont’d) § Antibiotics after obtaining cultures (e. g. , blood,

Collaborative Care Septic Shock (Cont’d) § Antibiotics after obtaining cultures (e. g. , blood, wound exudate, urine, stool, sputum) Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Septic Shock (Cont’d) § Glucose levels <150 mg/dl § Stress ulcer prophylaxis

Collaborative Care Septic Shock (Cont’d) § Glucose levels <150 mg/dl § Stress ulcer prophylaxis with histamine (H 2)-receptor blockers § Deep vein thrombosis prophylaxis with low-dose heparin or lowmolecular-weight heparin Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Neurogenic Shock § In spinal cord injury: Spinal stability n Treatment of

Collaborative Care Neurogenic Shock § In spinal cord injury: Spinal stability n Treatment of the hypotension and bradycardia with vasopressors and atropine n Fluids used cautiously as hypotension is generally not related to fluid loss n Monitor for hypothermia Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Anaphylactic Shock § Prevent! n n n Assess for allergies/adverse reactions Family

Collaborative Care Anaphylactic Shock § Prevent! n n n Assess for allergies/adverse reactions Family education Epinephrine Knowledge about signs/symptoms Be prepared for emergency measures § Epinephrine, diphenhydramine § Maintaining a patent airway Nebulized bronchodilators n Endotracheal intubation or cricothyroidotomy may be necessary n Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Collaborative Care Anaphylactic Shock (Cont’d) § Aggressive fluid replacement § Intravenous corticosteroids if significant

Collaborative Care Anaphylactic Shock (Cont’d) § Aggressive fluid replacement § Intravenous corticosteroids if significant hypotension persists after 1 to 2 hours of aggressive therapy Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Assessment § ABCs: Airway, breathing, and circulation Copyright © 2010, 2007, 2004, 2000,

Nursing Assessment § ABCs: Airway, breathing, and circulation Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Assessment (Cont’d) § Focused assessment of tissue perfusion n Vital signs n Peripheral

Nursing Assessment (Cont’d) § Focused assessment of tissue perfusion n Vital signs n Peripheral pulses n Level of consciousness n Capillary refill n Skin (e. g. , temperature, color, moisture) n Urine output Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Assessment (Cont’d) § Brief history n Events leading to shock n Onset and

Nursing Assessment (Cont’d) § Brief history n Events leading to shock n Onset and duration of symptoms § Details of care received before hospitalization § Allergies Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Diagnoses § Ineffective tissue perfusion: Renal, cerebral, cardiopulmonary, gastrointestinal, hepatic, and peripheral §

Nursing Diagnoses § Ineffective tissue perfusion: Renal, cerebral, cardiopulmonary, gastrointestinal, hepatic, and peripheral § Fear § Potential complication: Organ ischemia/dysfunction Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Planning § Goals for patient n Adequate tissue perfusion n Restoration of normal or

Planning § Goals for patient n Adequate tissue perfusion n Restoration of normal or baseline BP n Return/recovery of organ function n Avoidance of complications from prolonged states of hypoperfusion Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation § Health Promotion n Identify patients at risk (e. g. , elderly

Nursing Implementation § Health Promotion n Identify patients at risk (e. g. , elderly patients, those with debilitating illnesses or who are immunocompromised, surgical or accidental trauma patients) Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Health Promotion n Planning to prevent shock (e. g. ,

Nursing Implementation (Cont’d) § Health Promotion n Planning to prevent shock (e. g. , monitoring fluid balance to prevent hypovolemic shock, maintenance of handwashing to prevent spread of infection) Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Acute Interventions n Monitor the patient’s ongoing physical and emotional

Nursing Implementation (Cont’d) § Acute Interventions n Monitor the patient’s ongoing physical and emotional status to detect subtle changes in the patient’s condition n Plan and implement nursing interventions and therapy Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Acute Interventions n Evaluate the patient’s response to therapy n

Nursing Implementation (Cont’d) § Acute Interventions n Evaluate the patient’s response to therapy n Provide emotional support to the patient and family n Collaborate with other members of the health team when warranted Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Neurologic status: Orientation and level of consciousness § Cardiac status

Nursing Implementation (Cont’d) § Neurologic status: Orientation and level of consciousness § Cardiac status n Continuous ECG n VS, capillary refill n Hemodynamic parameters: central venous pressure, PA pressures, CO, PAWP n Ongoing assessment of CO Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Respiratory status n Respiratory rate and rhythm n Breath sounds

Nursing Implementation (Cont’d) § Respiratory status n Respiratory rate and rhythm n Breath sounds n Continuous pulse oximetry n Arterial blood gases n Many patients will be intubated and mechanically ventilated Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Urine output § Tympanic or pulmonary arterial temperature § Skin:

Nursing Implementation (Cont’d) § Urine output § Tympanic or pulmonary arterial temperature § Skin: Temperature, pallor, flushing, cyanosis, diaphoresis, piloerection § Bowel sounds Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Nasogastric drainage/stools for occult blood § I&O, fluid and electrolyte

Nursing Implementation (Cont’d) § Nasogastric drainage/stools for occult blood § I&O, fluid and electrolyte balance § Oral care/hygiene based on O 2 requirements § Passive/active range of motion Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Nursing Implementation (Cont’d) § Assess level of anxiety and fear n Medication PRN n

Nursing Implementation (Cont’d) § Assess level of anxiety and fear n Medication PRN n Talk to patient n Visit from clergy n Family involvement n Comfort measures n Privacy n Call light within reach Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Evaluation § Normal or baseline, ECG, BP, CVP, and PAWP § Normal temperature §

Evaluation § Normal or baseline, ECG, BP, CVP, and PAWP § Normal temperature § Warm, dry skin § Urinary output >0. 5 ml/kg/hr § Normal RR and Sa. O 2 ≥ 90% § Verbalization of fears, anxiety Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Case Study Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of

Case Study Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Case Study § 26 -year-old male arrives via paramedics to ED with multiple gun

Case Study § 26 -year-old male arrives via paramedics to ED with multiple gun shot wounds to abdomen § Unresponsive, BP 58/30, HR 146 Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Case Study (Cont’d) § Three units type O packed RBC given for profuse blood

Case Study (Cont’d) § Three units type O packed RBC given for profuse blood loss prior to surgery Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Case Study (Cont’d) § Surgery successful in removing bullets and repairing blood vessels §

Case Study (Cont’d) § Surgery successful in removing bullets and repairing blood vessels § Surgeon estimated he lost at least 2 L of blood prior to surgery § He is admitted to ICU Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Discussion Questions 1. What complications will you anticipate with this amount of blood loss?

Discussion Questions 1. What complications will you anticipate with this amount of blood loss? 2. What fluids can you expect to administer? Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.

Discussion Questions (Cont’d) 3. What medications will likely be ordered? 4. What should you

Discussion Questions (Cont’d) 3. What medications will likely be ordered? 4. What should you monitor hourly or every 2 hr? Copyright © 2010, 2007, 2004, 2000, Mosby, Inc. , an affiliate of Elsevier Inc. All Rights Reserved.