FOCUS LESSON BIOTECHNOLOGY INTRODUCTION 1 While genetic engineering

FOCUS LESSON : BIOTECHNOLOGY INTRODUCTION 1. While genetic engineering has positive benefits, there also concerns associated with widespread use of genetic engineering in agriculture. If many farmers begin to plant more genetically modified crops that have an increased tolerance to insects, which of the following may result? A. An increase in the use of pesticides B. A decrease in genetic diversity of the crops C. An increase in the contamination of the water supply D. A decrease in crop productivity on these treated fields 2. Biotechnology includes several laboratory techniques that have impacted the understanding of diseases that could lead to better treatments or cures. What would be the most beneficial and ethical use of biotechnology in medical research? A. Boosting the genetic yield of enzymes that would increase muscle strength in athletes B. Controlling the skin pigmentation genes to prevent freckles, moles, and birthmarks C. Producing “designer babies” that express the parents’ preferred eye or hair color D. Replacing mutated genes with functional ones to correct disorders such as diabetes

HOW IS SOCIETY INFLUENCED BY BIOTECHNOLOGY? SC. 912. L. 16. 10 EVALUATE THE IMPACT OF BIOTECHNOLOGY ON THE INDIVIDUAL, SOCIETY, AND THE ENVIRONMENT, INCLUDING MEDICAL AND ETHICAL ISSUES.

FOCUS LESSON : BIOTECHNOLOGY EXPLICIT INSTRUCTION Farmers have traditionally bred animals and plants to yield offspring with the best combination of characteristics (selective breeding) – examples: Breeding of dogs, cats, fish, cows, etc. Different variations of vegetables from the wild mustard plant Biotechnology, through genetic manipulation, is a similar labbased approach to selective breeding

FOCUS LESSON : BIOTECHNOLOGY EXPLICIT INSTRUCTION Manipulation of DNA in organisms has led to commercial production of biological molecules on a large scale production of (GMOs) genetically modified organisms has applications in medical treatment and scientific research (ex. HGH, insulin) DNA Fingerprinting - used for identifying suspects at crime scenes, paternity testing Genetic testing – used to identify carriers of specific diseases or conditions

FOCUS LESSON : BIOTECHNOLOGY GUIDED PRACTICE Discuss the scenario in your group, select an answer and provide a reasoning. 1. You've found out that the child you (or your wife) carries has the gene for dwarfism. A new therapy exists that may repair this gene before the child is born. What do you do? A. Allow the child to be born with the gene, and we will accept the child as is. B. Attempt the new therapy to repair the gene C. Terminate pregnancy 2. An agricultural company has found a way to make tomatoes 50% larger by splicing elephant genes into the tomatoes. Will you: A. Buy the tomatoes and have no problem eating them B. Probably not buy or eat the tomatoes C. Protest the company.

FOCUS LESSON : BIOTECHNOLOGY GUIDED PRACTICE Discuss the scenario in your group, select an answer and provide a reasoning. 3. Pet cloning is now available at the local mall. You used to have a pet dog named Charlie, but he died two years ago. Now you learn that you can get a new Charlie by just bringing in a sample of his hair. What do you do? A. Find a strand of Charlie's hair as soon as possible. Can't wait to see Charlie again! B. Let sleeping dogs lie. (Don't clone Charlie) 4. A company can now create test tube babies according to parent specifications. The company can make sure that your child has all the traits you desire - hair color, intelligence, athletic ability, etc. What do you do? A. Sign me up, I want my child to be perfect. B. I'd rather let nature take its course. C. We might adjust some things to make sure the child is healthy (and has no genetic abnormalities).

FOCUS LESSON : BIOTECHNOLOGY GUIDED PRACTICE Discuss the scenario in your group, select an answer and provide a reasoning. 5. You find out that you and your 6. Your family is known to have spouse are both carriers for a gene that could cause your children to be severely disabled. Your child has a 25% chance of developing this condition. What do you do? Huntington's disease. Huntington's is a disease that causes its victims to slowly lose their ability to speak, walk and function. Ultimately, Huntington's causes death. There is a test that will tell you whether you have the gene for Huntington's disease. What do you do? A. Choose not to have children, A. I would take the test, so that I better to adopt than risk it. B. Those aren't bad odds, we'd take the chance. would be better prepared for the future, and could make sure my family was taken care of. B. I would not want to know.

FOCUS LESSON : BIOTECHNOLOGY GUIDED PRACTICE Discuss the scenario in your group, select an answer and provide a reasoning. 7. Cloning technology is perfected. 8. A government organization is proposing to have all citizens of the US submit a sample of their hair so that their DNA can be scanned and kept on file. Each person's DNA would be kept in a national database so that police could access the DNA when a crime was committed. Do you? A clone can be made from adult tissue samples. You learn that you need a kidney transplant, but there are no donors available. A doctor suggests that you make a clone of yourself, so that the kidney would be a perfect match. What do you do? A. Support this legislation A. One is enough of me, I'll wait B. Oppose this legislation for a donor. B. Clone myself, two is better than one. C. Suggest the legislation be modified, only people with criminal records should be scanned.

FOCUS LESSON : BIOTECHNOLOGY INDEPENDENT PRACTICE Using SRE (statement, reason, & evidence), answer the following: (SRE) Statement – Reason - Explanation Statement State the correct answer in sentence format. Reason Provide a reason for why you selected the answer you chose. Provide a reason why you did not select the other answer option(s). Evidence What evidence was provided that helped you select the answer you chose or eliminate the other answer options (cite your source). How is society influenced by biotechnology?

FOCUS LESSON : BIOTECHNOLOGY QUIZ QUESTION #1 Suspect identification for violent crimes is important in law enforcement. Biotechnology is used in evidence procedures and has helped to free wrongly convicted innocent people. Which biotechnology technique is often used in forensics? A. fingerprint analysis from weapons and other crime scene objects B. crime scene fiber comparison to carpets, clothing, and furniture C. DNA manipulation to compare genetic samples from suspects and victims D. microscopic tests on recovered bullets and ones from test firing of guns

FOCUS LESSON : BIOTECHNOLOGY QUIZ QUESTION #2 The National Institute of Health was one government agency which coordinated The Human Genome Project, leading to the mapping of more than 20, 000 genes of the human genome in 2003. Which of the following describes the main benefit of completing The Human Genome Project? A. being able to clone humans B. designing new human genes C. patenting specific human genes D. identifying genetically-based diseases

FOCUS LESSON : BIOTECHNOLOGY QUIZ QUESTION #3 Consumer demand of certain popular fruits and vegetables has led to a decrease of individual food species. However, different versions of vegetables such as purple potatoes and striped tomatoes have become popular. Since genes for desirable characteristics can be added to plants, what genetic modification could lead to a drop in crop biodiversity? A. shifting the food web by adding pesticide resistance genes and forcing insects to find new foods B. increasing grain demand by improving vitamin content and cereal nutrition C. inserting a gene to ripen produce during market transportation, changing harvest times and crop production D. putting a salt tolerance gene into rice, increasing usable farm land previously flooded by ocean currents