FASD Indiana FASD Prevention Taskforce Working to Prevent

FASD Indiana FASD Prevention Taskforce Working to Prevent Fetal Alcohol Spectrum Disorders Through High School and Middle School Curricula This presentation was designed for use in Upper Level High School Science Classes.

FASD Indiana FASD Prevention Taskforce Fetal Alcohol Spectrum Disorders Why a person should NOT drink alcohol if she COULD get pregnant!

Fetal Alcohol Spectrum Disorders (FASD) FASD Possible Diagnoses + = – Fetal alcohol syndrome (FAS) – Partial FAS (p. FAS) – Alcohol-related neurodevelopmental disorder (ARND) – Alcohol-related birth defects (ARBD) FAE (fetal alcohol effects) is an older term used to describe the last three listed above.

FASD On any given day in the United States… • Approximately 11, 000 babies are born • 1 of these babies is HIV positive • 3 of these babies are born with muscular dystrophy • 4 of these babies are born with spina bifida • 10 of these babies are born with Down syndrome • 20 of these babies are born with FAS • 100 of these babies are born with a FASD From the Executive Summary of the IOM Report. FAS Community Resource Center. http: //www. come-over. to/FASCRC

FASD The Prevalence of FAS and FASD • The prevalence of FAS is estimated to be about 1 in 500 to 1 in 1000 births • The prevalence of FASD is estimated to be nearly 1 in 100 births Eustace LW 2003; Substance Abuse and Mental Health Services Administration; and the Centers for Disease Control and Prevention

FASD How much is too much? • The more alcohol consumed during pregnancy, the higher the risk for adverse effects – Binge drinking is particularly harmful! • No amount of alcohol has been proven ‘safe’ to consume during pregnancy • Every FASD is 100% preventable!

FASD What is a Drink? A Binge is four or more drinks on one occasion for a woman; five or more for a man A Drink is 12 ounces of beer, five ounces of wine, or 1. 5 ounces of hard liquor = =

FASD The Effect of Alcohol on a Baby’s Development • Alcohol freely crosses the placenta from the mother to the baby • Blood alcohol levels of the baby are equal to that of the mother, within minutes of consumption • The critical period is the entire pregnancy

FASD The Effect of Alcohol on a Baby’s Development Brain and nervous system Heart Limbs Lips and palate Eyes Ears Development of the brain is occurring throughout the pregnancy, which means that alcohol exposure at any point may cause brain damage. Figure from http: //www. fda. gov/cber/gdlns/rvrpreg_fig 1. gif

FASD The Diagnosis of FAS Defined by four criteria: 1. 2. 3. 4. Exposure to alcohol while in the womb Characteristic facial features Growth problems Involvement of the central nervous system (the brain)

FASD Facial Features: Smooth Philtrum and Thin Upper Lip Smooth philtrum (little to no groove above upper lip) Thin upper lip NOTE: Although these features are associated with fetal alcohol syndrome, they may also be seen in people who do not have a FASD.

FASD FAS Facial Features: Short Palpebral Fissures (Eye Openings) Eyes are measured from the outer corner to the inner corner

FASD The Effect of Alcohol on Growth • Alcohol consumption increases the risk for having a baby with growth problems • After birth, exposed children may continue to have a decreased growth rate and subsequent short stature Day and Richardson, 2004, AJMG 127 C: 28 -34. www. cdc. gov/growthcharts

FASD Alcohol Affects Overall Brain Size Brain of a healthy baby Brain of a baby exposed to alcohol Photo by Sterling Clarren, MD http: //www. come-over. to/FASbrain. htm

FASD Alcohol Affects Brain Structure • Certain parts of the developing brain are highly susceptible to damage by exposure to alcohol http: //pubs. niaaa. nih. gov/publications/arh 284/205 -212. htm

FASD The Effect of Alcohol on the Corpus Callosum • The corpus callosum is a transverse band of nerve fibers that connect the two hemispheres of the brain • An underdevelopment of the corpus callosum is frequently reported in kids with a FASD http: //pubs. niaaa. nih. gov/publications/arh 284/205 -212. htm Spadoni AD, et al. 2007

FASD The Effect of Alcohol on the Corpus Callosum Normal Absent • Corpus callosum abnormalities have been linked to deficits in attention, intellectual functioning, verbal memory, and executive and psychosocial functioning Spadoni AD, et al. 2007

FASD The Effect of Alcohol on the Hippocampus • The hippocampus, which plays a critical role in memory formation, may also be affected in individuals with a FASD http: //pubs. niaaa. nih. gov/publications/arh 284/205 -212. htm Spadoni AD, et al. 2007

FASD The Effect of Alcohol on the Cerebellum • The cerebellum, which is involved in motor abilities, balance, and sensory perception, may be smaller than average in affected individuals http: //pubs. niaaa. nih. gov/publications/arh 284/205 -212. htm Spadoni AD, et al. 2007

FASD The Effect of Alcohol on the Basal Ganglia • The basal ganglia are a group of nerve cells (including the caudate and lenticular nucleus circled on the diagram) located deep inside the brain • They are involved in movement and procedural learning • The basal ganglia are smaller than expected in kids with a FASD http: //pubs. niaaa. nih. gov/publications/arh 25 -4/288 -298. htm Spadoni AD, et al. 2007

FASD What is seen when the brain has been affected by exposure to alcohol?

FASD Prenatal Alcohol Exposure and the Central Nervous System • Cognitive deficits or developmental discrepancies – Low IQ (including mental retardation) – Significant developmental delays – Specific learning disabilities (esp. with math and/or visual spatial deficits) – Discrepancy between verbal and non-verbal skills – Slowed movements or reaction (slow information processing)

Prenatal Alcohol Exposure and the Central Nervous System FASD • Executive functioning deficits – – – – Poor organization, planning, or strategy use Concrete thinking Lack of inhibition Difficulty grasping cause and effect Inability to delay gratification Difficulty following multi-step instructions Poor judgment Inability to apply knowledge to new situations

FASD Prenatal Alcohol Exposure and the Central Nervous System • Motor functioning delays or deficits – – – – Delayed motor milestones Difficulty with writing or drawing Clumsiness Balance problems Tremors Poor dexterity Poor suck in infancy

FASD Prenatal Alcohol Exposure and the Central Nervous System • Attention and hyperactivity – – – – Inattentive Easily distracted Difficulty calming down Overly active Difficulty completing tasks Trouble with transitions May have “on” and “off” days

FASD Prenatal Alcohol Exposure and the Central Nervous System • Social skills problems – – – – Lack of stranger fear Naiveté and gullibility Easily taken advantage of Inappropriate choice of friends, preferring younger friends Immaturity Superficial interactions Inappropriate sexual behaviors Difficulty understanding the perspective of others

FASD Prenatal Alcohol Exposure and the Central Nervous System • Other – Sensory problems – Pragmatic language problems (difficulty reading facial expressions) – Memory deficits – Difficulty responding appropriately to common parenting practices

Normal FAS To summarize, differences in brain function may appear as: – Taking longer to process information – Problems remembering things – Difficulties with generalizing, forming associations, and understanding abstract concepts – Problems understanding consequences or cause-and-effect Malbin D. 2002

A teenager with a FASD, who is 18 years old, may function at the level of a child or adolescent Emotional maturity 6 years Comprehension 6 years Social skills Concepts of money and time Living skills Reading ability Physical maturity Skill 7 years 8 years 11 years 16 years 18 years Developmental Age Equivalent Adapted from: www. efsmanitoba. com/html/Final%20 Paper%20 Defining%20 Needs%20 of%20 women%20 with%20 FAS_E 2. htm

FASD Primary vs. Secondary Disabilities • Primary disabilities result from brain damage due to the alcohol exposure • Secondary disabilities develop over time due to lack of intervention and unmet needs – They are believed to be preventable

FASD Secondary Disabilities in FASD • Mental health issues • Disrupted school experiences • Inappropriate sexual behavior • Trouble with the law • Confinement in jail or treatment facilities • Alcohol and drug problems • Dependent living • Employment problems http: //come-over. to/FAS/

Secondary Disabilities www. fasdcenter. samhsa. gov; Streissguth AP, et al. 2004

FASD The Long Term Consequences of FAS • Only 3% of children lived with biological mother • Poor behavior was common • Average academic function was between 2 nd and 4 th grade • Independent living was uncommon among adults with FAS Streissguth et al. 1991

FASD For More Information • Fetal Alcohol Spectrum Disorders: Trying Differently Rather Than Harder, by Diane Malbin, MSW. Available at www. FASCETS. org. • Fetal Alcohol Syndrome: A Parents Guide to Caring for a Child Diagnosed with FAS, by Leslie Evans, MS, et al. Available for download at http: //otispregnancy. org/pdf/FAS_booklet. pdf • Fetal Alcohol Syndrome, Fetal Alcohol Effects: Strategies for Professionals, by Diane Malbin, MSW. Hazelden Foundation, Center City, MN. • Fetal Alcohol Syndrome: Practical Suggestions and Support for Families and Caregivers, by Kathleen Tavenner Mitchell, MHS, LCADC, and the National Organization on Fetal Alcohol Syndrome. Available at http: //www. nofas. org/estore

FASD • • • References Alan Guttmacher Institute. Facts on American teens’ sexual and reproductive health. www. guttmacher. org/pubs/fb_ATSRH. htm The Centers for Disease Control and Prevention. Fetal alcohol spectrum disorders. www. cdc. gov/ncbddd/fasprev. htm Day NL and Richardson GA. 2004. An analysis of the effects of prenatal alcohol exposure on growth: A teratologic model. American Journal of Medical Genetics Part C. 127 C: 28 -34. Eustace LW, et al. 2003. Fetal alcohol syndrome: A growing concern for healthcare professionals. Journal of Obstetric, Gynecologic, and Neonatal Nursing. 32: 215 -221. The Institute of Medicine. 1996 Report on FAS. http: //www. come-over-. to/FAS/ IOMsummary. htm Lupton C, et al. 2004. Cost of fetal alcohol spectrum disorders. American Journal of Medical Genetics Part C. 127 C: 242 -50. Mattson SN, et al. Teratogenic effects of alcohol on brain and behavior. National Institute on Alcohol Abuse and Alcoholism. http: //pubs. niaaa. nih. gov/publications/ arh 25 -3/185 -191. htm Spadoni AD, et al. 2007. Neuroimaging and fetal alcohol spectrum disorders. Neuroscience and Biobehavioral Reviews 31: 239 -245. Streissguth AP, et al. 1991. Fetal alcohol syndrome in adolescents and adults. Journal of the American Medical Association. 265(15): 1961 -7. Streissguth AP, et al. 2004. Risk factors for adverse life outcomes in fetal alcohol sydnrome and fetal alcohol effects. Developmental and Behavioral Pediatrics 25(4): 228 -238. Substance Abuse and Mental Health Services Administration Fact Sheets. http: //www. fasdcenter. samhsa. gov/grab. Go/fact. Sheets. cfm

FASD Helpful Websites • National Organization on Fetal Alcohol Syndromewww. nofas. org • Fetal Alcohol Syndrome, Education and Training Services, Inc. - www. fascets. org • The FASD Center for Excellence, Substance Abuse and Mental Health Services Administrationwww. fascenter. samhsa. gov • FASlink- http: //www. acbr. com/fas/ • The Arc- http: //www. thearc. org/fetalalcohol. html • The Centers for Disease Control and Preventionhttp: //www. cdc. gov/ncbddd/fas/default. htm

FASD Indiana Resources • The Fetal Alcohol Syndrome Center of Indiana - Indiana University Medial Center 975 West Walnut Street, IB 130 Indianapolis, IN 46202 Phone: 317 -274 -2450 Fax: 317 -274 -2387 Provides diagnosis, education and patient advocacy for those affected with prenatal alcohol exposure. • CNS - Center for Neurobehavioral Sciences 3010 E. State Ft. Wayne, IN 46805 Phone: 260 -471 -2300 Toll Free: 1 -800 -901 -8416 Provides therapy, education and patient advocacy for those affected with prenatal alcohol exposure. Organizes a support group for parents and caregivers (and other interested parties) of those with a FASD.

FASD Indiana Resources • Indiana Department of Health - IN Perinatal Network (IPN), Prenatal Substance Use Prevention Program (PSUPP) 2 N Meridian Street; Indianapolis, IN 46204 Phone: 317 -233 -1269 Fax: 317 -233 -1300 Referrals and early intervention for substance-using pregnant women. Training for professionals. • Indiana Protection and Advocacy Services 4701 N Keystone Avenue, Suite 222, Indianapolis, IN 46205 Phone: 800 -622 -4845 or 317 -722 -5555 Fax: 317 -722 -5564 Statewide agency for persons with developmental disabilities. www. in. gov/ipas

www. health. state. mn. us/fas/catalog

Slides developed by: Lisa J. Spock, Ph. D. , C. Gordon Mendenhall, Ed. D. Assisted by: David D. Weaver, M. D. Becky Kennedy, M. Ed. James M. Ignaut, M. A. , M. P. H. , C. H. E. S. Supported by: Indiana University School of Medicine Indiana State Department of Health Indiana Department of Education University of Indianapolis