EXTENDED DEPTH OF FOCUS WITH INDUCED SPHERICAL ABERRATION

EXTENDED DEPTH OF FOCUS WITH INDUCED SPHERICAL ABERRATION IN LIGHT ADJUSTABLE IOLs Pablo Artal, Eloy Villegas, Encarna Alcón, Inés Yago*, Elena Rubio*, José M. Marín* LABORATORIO DE OPTICA, UNIVERSIDAD MURCIA, SPAIN DE * Hospital Virgen de la Arrixaca, Murcia, SPAIN Supported by: Reserch funding and consulting reimbuserment provided by Calhoun Vision, USA

$* Light-adjustable intraocular lenses (LALs)* allow nearly PERFECT refractive outcomes, but also… customized near$

* Light-adjustable intraocular lenses (LALs)* allow nearly PERFECT refractive outcomes, but also… customized near vision by extended depth of focus with induced spherical aberration.

Spherical aberration increases depth of focus

LAL secondary treatments to induce spherical aberration (asphericity) increasing depth of focus (See example of LAL full treatment in next slide)

Secondary adjustment Primary adjustment Inducing spherical correcting defocus aberration & astigmatism Two weeks Surgery eye’s wave-fronts (examples) lock-ins

Patients were implanted bilaterally with LALs One eye was set to near emmetropia and in the fellow eye negative spherical aberration was induced

Visual acuity was measured using a computer-assisted procedure both monocularly (each eye separately) and binocularly Refraction and spherical aberration measured in each patient with a Hartmann-Shack wavefront sensor

and with letters on a micro-display placed at: 60 cm 40 cm 30 cm

Example of induction of negative spherical aberration in LALs Pre-adjusment Post-lockin 2 Myopic M 1 SA 3_60 Aspheric F 4. 7_b 0. 5 Z 12=+0. 12 mm Z 12 =-0. 20 mm > |-0. 3| mm

Visual acuity as a function of object distance Monocular (“far” eye) Monocular (“near” aspheric eye) Binocular vision 20/20 Z 12[-0. 14, -0. 24 mm] (sample 4) 20/25 20/30 J 1 J 2 20/40 J 3

Visual acuity as a function of object distance Binocular vision 20/20 Z 12[-0. 14, -0. 24 mm] (sample 4) 20/25 20/30 J 1 J 2 20/40 J 3

Conclusions - The use of the LALs as an advanced and fully customized approach to produce extended depth of focus modifying the eye’s asphericity has been demonstrated. - In a group of 4 patients, the average binocular visual acuity was 1. 1 for far and J 1 or better for intermediate and near distances. - The particular amounts of spherical aberration and defocus can be personalized to maximize quality of vision at all distances.