Exploration of EarthAbundant Transition Metals Fe Co Ni

Exploration of Earth-Abundant Transition Metals (Fe, Co, Ni) as Catalysts in Unreactive Chemical Bond Activations Bo Su, Zhi-Chao Cao, and Zhang-Jie Shi Reporter: Li Li Superbisor: Yong Huang 2015 -12 -29 Acc. Chem. Res. 2015, 48, 886

Concept

Inert chemical bond activation logic

Table Fe catalysis Fe-catalyzed C-O activation Co catalysis Co-catalyzed C-O activation Ni catalysis Ni-catalyzed eheric C-O activation Ni-catalyzed esteric C-O activation Ni-catalyzed C-O activation of aryl/alkenyl carbamates. Ni-Catalyzed C-O bond activation of phenolates Ni-Catalyzed C-O activation of benzylic alcohols

Fe catalysis Fe-catalyzed C-O activation J. Am. Chem. Soc. 2009, 131, 14656 -14657.

Fe catalysis Fe-catalyzed C-O activation Chem. Commun. 2013, 49, 7794 -7796.

Fe catalysis

Co catalysis C-O activation J. Chem. Soc. D , 1970, 847 Eur. J. Org. Chem. 2005, 989 J. Am. Chem. Soc. 2012, 134, 14638

Ni catalysis C-O activation Chem. Commun. 2008, 1437 J. Am. Chem. Soc. 2008, 130, 3268

Ni catalysis Rational Design of Selective C-O Activation of Carboxylate Chem. Lett. 1976, 1091

Ni catalysis Selective C−O Activation of Aryl Carboxylates J. Am. Chem. Soc. 2008, 130, 14468 Chem. Eur. J. 2010, 16, 5844 Angew. Chem. , Int. Ed. 2008, 47, 10124

Ni catalysis Tentative Mechanism of the Ni-Catalyzed Selective C-O Activation of Aryl Carboxylates

Ni catalysis sp 3 C-O Activation of α-Pivaloxyl Ketones Chem. Commun. 2011, 47, 7224

Ni catalysis Proposed Mechanism of the Ni-Catalyzed sp 3 C-O Activation of α-Pivaloxyl Ketones

Ni catalysis Selective sp 3 C-O Activation of Aryl/Alkenyl Carbamates Org. Lett. 2010, 12, 884

Ni catalysis C-O Activation of Magnesium Naphtholates Angew. Chem. Int. Ed. 2010, 49, 4566

Ni catalysis Rational Design of the New Mutual Activation Concept

Ni catalysis C-O Activation of Sodium Naphtholates Angew. Chem. Int. Ed. 2011, 50, 7097

Ni catalysis Possible Role of Et 3 B in the Mutual Activation.

Ni catalysis sp 3 C-O Bond Activation of Benzylic Alcohols J. Am. Chem. Soc. 2012, 134, 14638

Summary Fe-, Co-, and Ni-catalyzed C-O acivation Unveiling the relationship between their structures and their reactivity are highly needed Earth abundant transition-metal catalysis VS late transition-metal Aliphatic C-H transformations Designing new ligand for different condition

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