Evaluation of prognostic factors among patients with chronic

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Evaluation of prognostic factors among patients with chronic graft-versus-host disease by Jose A. Pérez-Simón,

Evaluation of prognostic factors among patients with chronic graft-versus-host disease by Jose A. Pérez-Simón, Gabriel Afram, Rodrigo Martino, Jose L Piñana, Teresa Caballero-Velazquez, Olle Ringden, David Valcarcel, Dolores Caballero, Mats Remberger, Yanira de Paz, Jordi Sierra, Jesús San Miguel, and Hans Hagglund haematol Volume 97(8): 1187 -1195 August 1, 2012 © 2012 by Ferrata Storti Foundation

Patients’ characteristics. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by

Patients’ characteristics. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

Chronic GVHD organ involvement. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 ©

Chronic GVHD organ involvement. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

Characteristics of c. GVHD among patients with classic versus overlap syndrome. Jose A. Pérez-Simón

Characteristics of c. GVHD among patients with classic versus overlap syndrome. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

Univariate and multivariate analysis for c. GVHD related mortality. Jose A. Pérez-Simón et al.

Univariate and multivariate analysis for c. GVHD related mortality. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

Univariate and multivariate analysis for OS-c. GVHD. Jose A. Pérez-Simón et al. Haematologica 2012;

Univariate and multivariate analysis for OS-c. GVHD. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

Landmark plots illustrating the impact of (A) the NIH severity score; (B) the ECOG

Landmark plots illustrating the impact of (A) the NIH severity score; (B) the ECOG ≥ 2, 1 and 0 performance status; (C) the platelet count <100 and >100× 109/L; and (D) the severity of gut involvement on the incidence of c. GVHD-related mortality. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

Landmark plot illustrating the impact of the new composite variable on the incidence of

Landmark plot illustrating the impact of the new composite variable on the incidence of c. GVHDrelated mortality. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

(A) Overall survival from c. GVHD diagnosis for patients with 1– 3 versus ≥

(A) Overall survival from c. GVHD diagnosis for patients with 1– 3 versus ≥ 4 organs involved (B) for patients with classic c. GVHD versus overlap syndrome and (C) for patients with delayed a. GVHD versus classic c. GVHD. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

(A) Overall survival from c. GVHD diagnosis for patients with mild, moderate or severe

(A) Overall survival from c. GVHD diagnosis for patients with mild, moderate or severe c. GVHD (B) for patients with ECOG 0, 1 and ≥ 2 (C) for patients with platelets <100 and >100× 109/L and (D) for patients with gut score 3, 2, 1 and 0. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation

Overall survival from c. GVHD diagnosis depending on the variable which resulted from combining

Overall survival from c. GVHD diagnosis depending on the variable which resulted from combining ECOG, platelets and gastrointestinal involvement. Jose A. Pérez-Simón et al. Haematologica 2012; 97: 11871195 © 2012 by Ferrata Storti Foundation