Environmental determinants of severity in sickle cell disease Slides: 5 Download presentation Environmental determinants of severity in sickle cell disease by Sanjay Tewari, Valentine Brousse, Frédéric B. Piel, Stephan Menzel, and David C. Rees haematol Volume 100(9): 1108 -1116 September 4, 2015 © 2015 by Ferrata Storti Foundation Global map of the presence or absence of the sickle cell mutation in representative population surveys, based on data from Piel et al. 20, overlaying the mean annual temperature (in °C) based on data from World. Clim (http: //www. worldclim. org/), last accessed. . . Sanjay Tewari et al. Haematologica 2015; 100: 1108 -1116 © 2015 by Ferrata Storti Foundation Bar graphs showing the mean number of admissions for the different quartiles of (A) maximum gust wind speed and (B) mean humidity. Sanjay Tewari et al. Haematologica 2015; 100: 1108 -1116 © 2015 by Ferrata Storti Foundation Maps of the distribution of patients with sickle cell disease in England France. Sanjay Tewari et al. Haematologica 2015; 100: 1108 -1116 © 2015 by Ferrata Storti Foundation Estimates of annual births with sickle cell anemia (SCA) in 2010 according to the gross national income (GNI) per capita, divided into four classes according to the World Bank income classification (2010): low income: US$1, 005 or less; medium low income: US. . . Sanjay Tewari et al. Haematologica 2015; 100: 1108 -1116 © 2015 by Ferrata Storti Foundation