Electrospinning Nanofibers for Scaffolding By Dan Tamayo What

Electrospinning Nanofibers for Scaffolding By: Dan Tamayo

What are Electrospun Nanofibers? Electrospun Nanofibers are polymer solutions that are pumped through a syringe They form an ultrafine fiber that are layered on top of each other to form a mesh This mesh can be used to culture and cultivate cells as a scaffold in tissue engineering

How it’s Done http: //www. jove. com/video/2494/electrospinningfundamentals-optimizing-solution-and-apparatusparameters 2: 23

Finished Nanofiber Scaffold

Uses Used for tissue engineering scaffolding Can be used to deliver medication

History of Electrospinning 1902 - Electrospinning was first discovered by Marley and Cooley 1934 - The apparatus was designed and patented 1940 - The design was perfected and a new apparatus was patented, this is the apparatus and technique we use today

State of the Art Technology Today there are ways that nanofibers can be electrospun while infused with medication. While these nanofibers biodegrade, the medication is evenly released throughout the body.

Limitations Research Difficult to do

Future We will be able to make scaffolding out of materials and chemicals that mimic human proteins and tissues identically. The optimal scaffold will be found to make cells grow, mature and direct cell migration to the best of their ability.

Work Cited Meng, Z & Zu, X (2011) Preparation and characterization of electrospun PLGA/gelatin nanofibers as a potential drug delivery system. Colloids and Surfaces B: Biointerfaces. 84 (1) 97 -102 Chinwe Nwachukwu, C (2010) Electrospinning protein nanofibers to control cell adhesion. University of South Florida Scholar Commons. 55 (3) Subbiah, h & Bhat, G (2005) Electrospinning of nanofibers. Applied Polymer Science. 96 (2) 557569