Pulmonary Embolism Clues: Sinus tachycardia S 1 Q 3 T 3 pattern Incomplete RBBB with R precordial T wave inversions
PE
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Brugada syndrome • • • Defined in 1992 by brothers Pedro and Josep Brugada in J Am Coll Cardiol Rare condition associated with sudden cardiac death (SCD) or ventricular fibrillation/polymorphic VT in structurally normal hearts Mean age of presentation: 35 -40 years; male predominance (notably in SE Asia where it is endemic) Familial with autosomal dominant inheritance Clinical presentation: syncope or SCD is most common initial event; typically occurs in sleep or in early morning ECG criteria: ST segment elevation in V 1 -V 3 with characteristic RBBB pattern Defect in sodium channel gene (SCN 5 A) on chromosome 3 Lifetime risk of SCD Consider ICDs; refer for genetic counseling