EBI Metabolomics and Bioinformatics Resources training workshop The
EBI Metabolomics and Bioinformatics Resources training workshop The Jackson Laboratory Thursday 18 th October 2012 Time Subject 09. 00 -09. 30 Introduction to EBI and EBI search 09. 30 -10. 30 Introduction to Ch. EBI Exercises 10. 30 -11. 00 Tea & Coffee/ break 11. 00 -12. 30 Ch. EBI: Searching and the Ch. EBI Ontology Exercises 12. 30 -13. 15 -14. 30 Lunch 14. 30 -15. 00 -15. 30 The Enzyme Portal, Int. Enz and Rhea Exercises Introduction to Metabo. Lights Tea & Coffee break 15. 30 -16. 00 Small molecules and PDBe 16. 00 -17. 00 Introduction to Ch. EMBL Exercises Course Feedback
The EBI Enzyme Portal Cheminformatics and Metabolism Team
Enzyme-related resources at the EBI MACi. E Inter. Pro
The Enzyme Portal integrates EBI’s enzyme resources into a single access point MACi. E Enzyme Portal Inter. Pro
Stakeholders' Requirements Data source to be acknowledged u. Free and open access to the data u. Scope: Enzyme related resources u
User Requirements Gathering u u u Target users User roles User interviews User workflow analysis User workshop ü ü u Users' expectation on the content Users' desired functionalities High level user requirements captured
User Requirements - Functionalities u Search ü ü ü u Free text Chemical structure Sequence Compare enzymes Browse ü ü EC Hierarchy Chemical structure Disease Taxonomy Customised export
User Requirements - Content u u u Enzyme Headline Pathway Reaction Structure-Function Diseases and Drugs References
Enzyme Portal home page
Enzyme Portal Results Page
Enzyme Portal Results Page
Enzyme Portal Entry Summary
Enzyme Portal Protein Structure
Enzyme Portal Reactions/Pathways
Enzyme Portal Reactions/Pathways
Enzyme Portal Small Molecules
Enzyme Portal Small Molecules
Enzyme Portal Diseases
Enzyme Portal Literature
Work in progress u Search by sequence or chemical structure u Browsing u Enzyme comparison u Customised downloads
As a result of new data releases, question 4 should now read: Search for “Deoxyribonucleic methylase” and filter results to see only human. Click on the seventh result in the list and see how many drugs and bioactive compounds have been described for this enzyme. Time for exercises……. 22 13/01/2022
- Slides: 21