DRUGS OF ADDICTION Ken Roy MD Addiction Recovery

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DRUGS OF ADDICTION Ken Roy, MD Addiction Recovery Resources of New Orleans Tulane Department

DRUGS OF ADDICTION Ken Roy, MD Addiction Recovery Resources of New Orleans Tulane Department of Psychiatry River Oaks Hospital 504 -780 -2766 www. arrno. org

Why are Drugs Addicting? n n Cause pleasure In our pleasure and reward system

Why are Drugs Addicting? n n Cause pleasure In our pleasure and reward system

The Unfortunate Truth n n After tonight you will know more than your doctor

The Unfortunate Truth n n After tonight you will know more than your doctor knows about drugs of addiction This is your disease, and your responsibility to get and stay well Everyone will need medical care in recovery You cannot trust that your doctor knows what to do to keep you in recovery

Why This is an “Easy Study” n n We have very few “natural” neurotransmitters

Why This is an “Easy Study” n n We have very few “natural” neurotransmitters that make us feel good All of the plant derived and synthetically compounded chemical that fit on the same receptor as a “natural” chemical form a CLASS of addicting drugs

How Easy It Is n Only three major Classes n n Sedative Hypnotics Stimulants

How Easy It Is n Only three major Classes n n Sedative Hypnotics Stimulants Opiates And a “wastebasket” Class n Hallucinogens

Classes n All drugs in a Class are: n n Cross addicting Cross tolerant

Classes n All drugs in a Class are: n n Cross addicting Cross tolerant Cross relapsing Drugs in a Class result in similar: n n n Intoxication Detoxification Overdose

Sedative Hypnotics n n Alcohol Benzodiazepines n n Good old Barbs + Fiorinal, Esgic,

Sedative Hypnotics n n Alcohol Benzodiazepines n n Good old Barbs + Fiorinal, Esgic, etc. Other sleepers n n Valium, Ativan, Xanax, Rohypnol, Restoril Barbiturates n n GABA Quaalude, Doriden, Placidyl, Ambien Miscellaneous n GHB, Soma

Stimulants n n Cocaine + Crack Cocaine Amphetamines n n Noradrenalin Good old speed

Stimulants n n Cocaine + Crack Cocaine Amphetamines n n Noradrenalin Good old speed + Crystal = Crank + Ice MDA, MDMA, Adderall Ritalin, Cylert Decongestants n OTC Diet Pills

Opiates n Injectable n n Morphine, Heroin, Demerol, Dilaudid, Stadol, Nubain, Buprenorphine Oral medications

Opiates n Injectable n n Morphine, Heroin, Demerol, Dilaudid, Stadol, Nubain, Buprenorphine Oral medications n n Endorphins #2 -4, Vicodin, Lorcet, Lortab, Norco, Percodan, Oxy. Contin, Ultram, Darvon Methadone

Hallucinogens n LSD, Psilocybin, Mescaline n n Indirectly affect Dopamine through Serotonin Marijuana n

Hallucinogens n LSD, Psilocybin, Mescaline n n Indirectly affect Dopamine through Serotonin Marijuana n n Various Has it’s own neurotransmitter PCP, Ketamine n General anesthetics in high doses

Drugs of Abuse n Medications n n Inhalants n n Benadryl, Elavil, Seroquel, Prednisone

Drugs of Abuse n Medications n n Inhalants n n Benadryl, Elavil, Seroquel, Prednisone Glue, paint, whiteout, toluene, gasoline, N 2 O Caffeine

Cross Addiction Between Classes n n n Occasionally occurs, based on availability or change

Cross Addiction Between Classes n n n Occasionally occurs, based on availability or change in preference Most often use results in relapse to original drug of choice Connects through the Locus Ceruleus n A small area in the brain that produces all of the brain adrenalin, or Norepinephrine

Take Home Messages n n Use of any addicting drug during or before recovery

Take Home Messages n n Use of any addicting drug during or before recovery produces addict thinking Most addicting drugs are prescribed medications There is a chance of switching addictions to another class There is a greater danger of relapse to the original drug of choice.

If You Have to Use n n Have a plan to become abstinent again

If You Have to Use n n Have a plan to become abstinent again Have a safety net n n Someone who will pull you back, no matter what Build your spiritual “Bank Account” n By frequent meeting attendance – for the foreseeable future