DrugEluting Stents in AMI RCTs Trial DES BMS

Drug-Eluting Stents in AMI (RCTs) Trial DES BMS N Angio Follow-Up Primary EP STRATEGY 1 Cypher Bx Vel 175 Yes 8 mo D, Re. MI, CVA, or TVR TYPHOON 2 Cypher Any 700 Yes 12 mo TVF SESAMI 3 Cypher Bx Vel 320 Yes 12 mo restenosis PASSION 4 Taxus Exp 2/Lib 620 No 12 mo D, Re. MI, TVR 1. Valgimigli M et al. JAMA 2005; 293: 2109 -2117. 2. 3. Menichelli M. Euro. PCR 2006. Clinical Trial Results. org 2. Spaulding C et al. NEJM 2006; 355: 1093 -104. 4. Laarman GJ et al. NEJM 2006; 355: 1105 -13. M Leon, TCT 2006

Drug-eluting Stents in AMI (RCTs) Mortality % All p=NS STRATEGY 8 mo n=175 Clinical Trial Results. org TYPHOON 12 mo n=700 SESAMI 12 mo n=320 PASSION 12 mo n=620 M Leon, TCT 2006

Drug-eluting Stents in AMI (RCTs) Reinfarction % All p=NS STRATEGY 8 mo n=175 Clinical Trial Results. org TYPHOON 12 mo n=700 SESAMI 12 mo n=320 PASSION 12 mo n=620 M Leon, TCT 2006

Drug-eluting Stents in AMI (RCTs) Stent thrombosis % All p=NS STRATEGY 8 mo n=175 Clinical Trial Results. org TYPHOON 12 mo n=700 SESAMI 12 mo n=320 PASSION 12 mo n=620 M Leon, TCT 2006

Drug-eluting Stents in AMI (RCTs) Target lesion revascularization p=0. 006 p<0. 001 % p=0. 23 STRATEGY 8 mo n=175 Clinical Trial Results. org TYPHOON 12 mo n=700 SESAMI 12 mo n=320 PASSION 12 mo n=620 M Leon, TCT 2006