Does Maternal Age Impact Nuchal Translucency Utilization since

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Does Maternal Age Impact Nuchal Translucency Utilization since the Introduction of Cell. Free DNA

Does Maternal Age Impact Nuchal Translucency Utilization since the Introduction of Cell. Free DNA LL Thornburg MD, LD Platt, MD, GT Toland MD, L Dugoff MD, J Mcintosh MD, K Fuchs MD, M Norton MD, B Bromley, MD on behalf of Perinatal Quality Foundation OBJECTIVE To assess changes in NT volume for patients > 35 years old with both singleton & twin pregnancies since introduction of cf. DNA screening METHODS: Review of total NTQR volumes 2012 -18 for singleton and twin pregnancies, stratified by age <35 vs. >35 y/o at delivery RESULTS: NT screens 2012 -18 for singletons & twins Singletons <35 yo Singletons ≥ 35 yo Twins <35 yo Twins≥ 35 yo 9, 000 350000 8, 000 Singleton NT Scans 400000 250000 5, 000 200000 4, 000 150000 3, 000 100000 2, 000 50000 1, 000 0 0 2012 2013 2014 2015 2016 2017 2018 Twin NT Scans 6, 000 Singleton NT scans 2012 -2018 # of NT scans/yr <35 There has been a significant reduction NT screening performed annually for both singleton & twin patients > 35 years old since the introduction of cell free DNA screening % change vs. 2012 # of NT scans/yr >35 % change vs. 2012 111, 308 Twin NT scans 2012 -2018 # of NT scans/yr <35 % change vs. 2012 7945 # of NT scans/yr >35 % change vs. 2012 329, 111 4, 053 2013 348562 +5. 9% 90378 -18. 8% 8230 +3. 6% 3606 -11. 0% 2014 354783 +7. 8% 77923 -29. 9% 8075 +1. 6% 3206 -20. 9% 2015 339659 +3. 2% 68918 -38. 1% 7490 -5. 7% 2807 -30. 7% 2016 300252 -8. 8% 60383 -45. 8% 6713 -15. 5% 2407 -40. 6% 2017 299341 -9. 1% 59859 -46. 2% 6506 -18. 1% 2361 -41. 8% 2018 274125 -16. 7% 56885 -48. 9% 5726 -27. 9% 2026 -50. 0% • For singletons & twins <35 • Little variation in the annual NT volume 2012 to 2017 • Significant drop after 2016 for singletons; 2017 for twins, p<. 01 • For singletons & twins >35 7, 000 300000 Changes in NT scan volume twins and singletons by Maternal Age • Singletons dropped significantly every year after 2016 (p<. 01) • Twins dropped significantly every year after 2012 (p<. 0001) • Since 2012, annual NT volume for AMA singletons has decreased by 48. 9% while twins has decreased by 50%