Do Maternal Characteristics Affect Nuchal Translucency Variation Nuchal

Do Maternal Characteristics Affect Nuchal Translucency Variation? Nuchal Translucency Quality Review program: 5 million results L Dugoff MD, H Cuckle MD, LD Platt MD, K Fuchs MD, J Mc. Intosh MD, J Spitz MPH, RDMS, B Bromley MD, LL Thornburg MD on behalf of Perinatal Quality Foundation OBJECTIVE: To evaluate the relationship between NT median Mo. M and maternal characteristics from NT data collected 1/2005 -3/2019 Maternal characteristics including age, weight, race/ethnicity and fetal number significantly affect NT median Mo. Ms. RESULTS: • Total of 5, 234, 950 NT imaging scans performed by 9340 providers at 3319 sites. • In multiple regression analysis variables remained statistically significant except IVF (P=0. 28). • For subset of 2, 547, 258 results with complete information Mo. Ms were recalculated dividing the observed NT Mo. M by the expected NT Mo. M, from the regression equation, with the overall median reduced by 2%. RESULTS: CONCLUSIONS: • Maternal characteristics including maternal age, weight, race/ethnicity and fetal number significantly affect NT median Mo. Ms. • It is critical that providers submit complete data for these variables to laboratories with the NT to optimize the calculation of Down syndrome risk. Data evaluated by wilcoxon Rank Sum Test, ANOVA, multiple regression