DNA Foldable Directions Fold 3 pieces of paper

DNA Foldable Directions: • Fold 3 pieces of paper, so you have 5 layered flaps • Write “DNA” on the top flap as a title

On each flap write: 1. 2. 3. 4. 5. DNA Basics & Organization DNA Structure & Function DNA Replication RNA Structure & Function Comparing DNA & RNA

1. DNA Basics & Organization

(Inside) On Top Half of 1 st Flap write: 1. Make the following flow chart: Cell Nucleus Chromosome DNA Gene Segment 2. Glue in the following picture below it of DNA

(Inside) On Bottom Half of 1 st Flap write: DNA stands for “Deoxyribonucleic acid” (type of organic molecule) DNA is the instructions for making proteins that carry out life functions

2. DNA Structure & Function

(Inside) On Top Half of 2 nd Flap write: Directions: Write “DNA STRUCTURE” Cut out panel and glue into flap 1. 2. Color the following: 3. • • • Green= Phospahte Group Red= Sugar Blue=Nitrogenous bases Yellow=Nucleotide Purple= Sugar-Phosphate backbone DNA is has a double helical shape!

(Inside) On Top Bottom Half of 2 nd Flap write: Directions: 1. 2. Write “DNA FUNCTION” Make the following table: Function: Facts: Storage of Genetic Code • Passing of Traits • double stranded sugar-phosphate backbone • internal code (nitrogenous bases are protected by sugar-phosphate backbone) • coiled tightly to allow for more surface area meaning more room to store genetic code nitrogen bases are complementary (A or adenine always bonds with T or thymine; C or cytosine always bonds with G or guanine) • weak hydrogen bonds hold bases togetherallow for ease during replication

3. DNA Replication

(Inside) On Top Half of 3 rd Flap write: Directions: 1. Cut out panel and glue into flap 2. Color the following in picture #1: • • Green= Parent Strand Yellow= Complementary Strand Outline the following: in picture #2: 3. • • #1 Red = Leading strand Blue = Lagging strand #2

(Inside) On Top Bottom Half of 3 rd Flap write 1. 2. Write “Steps of DNA Replication” Make the following flow chart: 1. DNA unwinds with help of protein helicase, this breaks weak hydrogen bonds between bases 2. The protein primase attached to the parent strand, this helps bind (attach) new nucleotides Leading Strand ONLY! 3. Elongation DNA protein polymerase reads template strand continuously adds new nucleotides that are complementary to the parent strand Lagging Strand ONLY! 5. DNA Termination 6. DNA repairs itself 4. DNA primers are removed & DNA ligase adds sugars and phosphates in gaps made by fragments 3. DNA primase adds more primers, DNA is elongated in short segments (okazzki fragments) by DNA polymerase and then is

4. RNA Structure & Function

(Inside) On Top Half of 4 th Flap write: Directions: 1. 2. Write “RNA STRUCTURE” Cut out pictures, glue into flap and label types of RNA m. RNA t. RNA r. RNA

(Inside) On Top Bottom Half of 4 th Flap write: Directions: 1. 2. Write “RNA FUNCTION” Make the following table: Type of RNA: Function: m. RNA “messenger” • r. RNA “ribosomal” • t. RNA “transfer” • makes a copy of DNA in the nucleus • travels from nucleus cytoplasm ribosome • bases in m. RNA are read in sets of 3 = codon “home” of protein synthesis= m. RNA brings code, t. RNA brings amino acids and r. RNA puts the two together to make protein gathers amino acids • travels to the ribosome • contains a set of 3 bases in t. RNA (anticodon)