DNA Damage and Repair 906113 DNA Damage a

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DNA Damage and Repair 畜產四 杜佩玲 906113

DNA Damage and Repair 畜產四 杜佩玲 906113

DNA Damage a. single base changes 1. Deamination 2. Replication error b. structural distortions

DNA Damage a. single base changes 1. Deamination 2. Replication error b. structural distortions 1. Ultraviolet irradiation 2. Alkylation 3. Depurination

DNA repair n n n Direct repair Excision repair ☆Mismatch repair Recombination repair ☆SOS

DNA repair n n n Direct repair Excision repair ☆Mismatch repair Recombination repair ☆SOS system

討論 TYPE OF DAMAGE events/cell/day % of total daily damage Single-strand break 120, 000

討論 TYPE OF DAMAGE events/cell/day % of total daily damage Single-strand break 120, 000 50. 9 N 7 -Methyl. Guanine 84, 000 35. 6 Depurination 24, 000 10. 2 Oxidized DNA 2, 880 1. 2 Depyrimidation 1, 320 0. 5 Cytosine deamination 360 0. 2 Double-strand breaks 9 0. 01

參考文獻 n n Gene VII, Chapter 14, Oxford University Press 現代遺傳學, 第二十章, 藝軒出版

參考文獻 n n Gene VII, Chapter 14, Oxford University Press 現代遺傳學, 第二十章, 藝軒出版

DNA DAMAGE AND REPAIR DNA Damage and RepairDNA DAMAGE AND REPAIR DNA Damage and Repair
DNA damage repair DNA damage and repair andDNA damage repair DNA damage and repair and
DNA damage repair and recombination MUTAGENESIS DNA DAMAGEDNA damage repair and recombination MUTAGENESIS DNA DAMAGE
DNA damage repair and recombination MUTAGENESIS DNA DAMAGEDNA damage repair and recombination MUTAGENESIS DNA DAMAGE
DNA damage repair and recombination MUTAGENESIS DNA DAMAGEDNA damage repair and recombination MUTAGENESIS DNA DAMAGE
Instability Mutation and DNA repair Mutations DNA repairInstability Mutation and DNA repair Mutations DNA repair
Instability Mutation and DNA repair Mutations DNA repairInstability Mutation and DNA repair Mutations DNA repair
Repair Types and positions Types of repair RepairRepair Types and positions Types of repair Repair
PATHOLOGY WOUND HEALINGREGENERATION AND REPAIR Repair Regeneration RepairPATHOLOGY WOUND HEALINGREGENERATION AND REPAIR Repair Regeneration Repair
Mechanisms DNA Repair I True repair defective DNAMechanisms DNA Repair I True repair defective DNA
DNA repair CMB Pp 209 215 DNA repairDNA repair CMB Pp 209 215 DNA repair
DNA Repair DNA repair refers to a collectionDNA Repair DNA repair refers to a collection
DNA Replication Repair DNA Replication Repair Dr KetkiDNA Replication Repair DNA Replication Repair Dr Ketki
DNA Repair DNA repair refers to a collectionDNA Repair DNA repair refers to a collection
Biochemistry 12412 VII DNA Repair A DNA damageBiochemistry 12412 VII DNA Repair A DNA damage
Damage Assessments Catherine Bohn Damage Assessments 2 DamageDamage Assessments Catherine Bohn Damage Assessments 2 Damage
DNA DNA RNA DNA RNA DNA RNA DNADNA DNA RNA DNA RNA DNA RNA DNA
DNA DNA cloning DNA Recombinant DNA Libraries DNADNA DNA cloning DNA Recombinant DNA Libraries DNA