Direct Sugar to Hydro Carbon Route Synthesized IsoParaffins

Direct Sugar to Hydro. Carbon Route Synthesized Iso-Paraffins from Hydroprocessed Fermented Sugars April 23, 2014 – ABLC Conference Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion Fernando Garcia Amyris, Inc. Senior Director, Scientific and Regulatory Affairs garcia@amyris. com

Status of SIP Fuel Qualification § DSHC route produces an Synthesized Iso-Paraffins (SIP) farnesane, for use in conventional Jet A-1 fuel • An industrial process combining fermentation and hydroprocessing steps • A high purity iso-paraffin grade (farnesane) as a blending component for conventional jet fuel • The neat molecule meets compositional specifications of SPK alternative jet fuel § Blends of farnesane in conventional jet fuel up to 50% meet the requirements of Aviation Turbine Fuels Containing Synthesized Hydrocarbons from ASTM D 7566 • Farnesane improves specific performance of the blends such as the freezing point, thermal stability and the net heat of combustion § Blends of farnesane in conventional jet fuel up to 20% meet the Fit-For-Purpose requirements described in ASTM D 4054 § Engines and aircraft were operated on blends at 10 and 20% • Data from engine and flight tests show no deviation between blend and baseline Jet A-1 • Data from Honeywell APU and P&W combustor tests support proposed specifications § Balloting ASTM approval for the use of farnesane at 10% blend in conventional jet fuel • Research Report has been successfully balloted • Presently balloting new Annex to ASTM D 7566 2 Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion, April 23, 2014

Amyris - Total partnership since June 2010 A specific partnership model to develop the value chain integrated from biomass to finished products Biomass Pre-treatment Fermentable raw materials Fermentation Molecules Ci Hj Downstream Processing Products § Synergy: assemble complementary technology, industrial and business capabilities Feedstock sourcing Synthetic biology Fermentation and chemical processes Trading & marketing Fuels 1 st generation in Brazil on sugar cane Bio-engineering of micro -organisms Track record for strain improvement Competitive molecules Leading to 2 nd generation R&D network Scale-up and industrial chemistry Access to markets § Differentiating technology: broad R&D collaboration (~$100 M) § Lab-to-market development: joint industrialization & commercialization 3 Special fluids Lubricants Chemicals Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion, April 23, 2014

Manufacturing process based on common industrial steps Purification § Fermentation § Microbe-catalyzed conversion of sugar: key is the development of a farnesene producing yeast § Production to date: >4 million liters of farnesene precursor § Farnesene plant with a capacity of up to 50 million liters per year at target efficiency in Brotas, Brazil § Downstream processing • • • Combination of hydroprocessing and separation operations Production to date: ~2 million liters of farnesane for diesel application Using diesel process slightly modified, farnesane aviation grade production to date for ASTM test purposes: ~ 30, 000 liters 4 Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion, April 23, 2014

Testing Collaboration with Industry § SNECMA Sa. M 146 engine test Performances, cold and hot starts and sub-idle & off-idle tests data did not present significant deviation between 10% blend and Jet A-1 § Lufthansa CFM 56 engine test The study concluded that in emission terms the farnesane blends perform similar to or better than the reference kerosene. In particle mass there is a clear reduction at all test points by increasing farnesane content. In performance terms, the farnesane blends perform similar to the reference kerosene. § Airbus experimental flights (A 321 with CFM 56 -5 B) The engine, supplied with the 10% blend, performed exactly like the x-wing sister engine fed with pure Jet A-1 § APU (Honeywell ) and Combustor tests (P&W) funding by DOT/FAA CLEEN) Analysis of fuel droplet size, ignition characteristics with combustor rigs, and APU cold and altitude starting in test chamber. 5 Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion, April 23, 2014

Commitment to Quality § Air Total • High-quality aviation fuels, under the most stringent Safety and Environmental standards • Complete range of services dedicated to aviation (technical inspections, refueling cards, etc. ) § SIP Fuel Assays • 19 assays with 30 characteristics • Only nine assays are common with commercial Jet A-1 • Qualifying labs that run GC farnesane purity § Process Quality Control Plan (QCP) An end-to-end (Farnesene-to-Jet Grade Fane Delivery) QCP has been developed, reviewed with the Total Quality team and is currently being implemented at Brazil operations based on ‘guard banding’ the Product specs by 3*Sigma of assay variation 6 Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion, April 23, 2014

Commitment to Quality: 3 rd Party Lab Validation § Safety Assessment § ISO 17025 Section 4: Management Requirements Management & document control systems, NCR processes (including cause analysis, CAPA implementation and monitoring), training processes and records, internal/external audits § ISO 17025 Section 5: Technical Requirements SQC documentation, analyst expertise, instrumentation, maintenance programs, calibration processes, data records, test report formats and review process, data control, OOC processes § Test Method Performance Capability per ASTM Requirements: - Repeatability: based on replicate analysis - Reproducibility: based on inter-lab round robin assessment & SQC charts Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion, April 23, 2014

Amyris and Total contacts 8 § AMYRIS: garcia@amyris. com § TOTAL: olivier. rolland@total. com Moving Forward with Sustainable Alternative Jet Fuels Development and Qualification Panel Discussion, April 23, 2014