Differential Gene Expression Differential Gene Transcription n What

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Differential Gene Expression

Differential Gene Expression

Differential Gene Transcription n What are the major differences between prokaryotic and eukaryotic genes?

Differential Gene Transcription n What are the major differences between prokaryotic and eukaryotic genes?

Differential Gene Transcription

Differential Gene Transcription

Differential Gene Transcription

Differential Gene Transcription

Differential Gene Transcription

Differential Gene Transcription

Differential Gene Transcription

Differential Gene Transcription

Promoters n How do promoters work?

Promoters n How do promoters work?

Enhancer n How is an enhancer different from a promoter? Activates use of promoter

Enhancer n How is an enhancer different from a promoter? Activates use of promoter n Activates promoters on same strand n Doesn’t need to be adjacent to gene n Doesn’t need to be upstream n

Enhancer n n How can one identify presence of an enhancer? Why are they

Enhancer n n How can one identify presence of an enhancer? Why are they so important?

Transcription Factors n What are the major structural domains of these molecules? DNA-binding domain

Transcription Factors n What are the major structural domains of these molecules? DNA-binding domain n Trans-activating domain n Protein-protein interaction domain n

Transcription Factors n What is MITF? n Trans-activating domain n Protein-protein interaction domain n

Transcription Factors n What is MITF? n Trans-activating domain n Protein-protein interaction domain n DNA-binding domain n DNA

Transcription Factors n Why is PAX 6 such an important molecule?

Transcription Factors n Why is PAX 6 such an important molecule?

Silencers n What are silencers?

Silencers n What are silencers?

Transcriptional Control n n n Of what value is DNA methylation? How has this

Transcriptional Control n n n Of what value is DNA methylation? How has this been demonstrated experimentally? How does methylation work?

Transcriptional Control n What are insulators?

Transcriptional Control n What are insulators?

Transcriptional Control n n n How does dosage compensation influence transcription? What are Barr

Transcriptional Control n n n How does dosage compensation influence transcription? What are Barr bodies? How does this relate to calico cats?

RNA Processing n What is the difference between n. RNA and m. RNA?

RNA Processing n What is the difference between n. RNA and m. RNA?

RNA Processing n n How is differential splicing of n. RNA accomplished? What is

RNA Processing n n How is differential splicing of n. RNA accomplished? What is the difference between genome and proteome?

Translational Control n What are some of the factors that influence gene expression at

Translational Control n What are some of the factors that influence gene expression at the level of translation?

Translational Control

Translational Control

Posttranslational Regulation n What is meant by this level of regulation? n How can

Posttranslational Regulation n What is meant by this level of regulation? n How can it occur?

Controlling Gene Expression

Controlling Gene Expression

Controlling Gene Expression

Controlling Gene Expression

Controlling Gene Expression

Controlling Gene Expression