Different Genes Protein Primary Structure Different Primary Sequences

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Different Genes ~ Protein Primary Structure Different Primary Sequences ~ 3 D Structure Relative

Different Genes ~ Protein Primary Structure Different Primary Sequences ~ 3 D Structure Relative scale of conservation Genes << Primary Structure << 3 D Structure

Gene Bioinformatics Protein - Mechanism of action / biological role - Evolutionary studies, protein

Gene Bioinformatics Protein - Mechanism of action / biological role - Evolutionary studies, protein folding. . . - Therapeutic applications: drug/vaccine design - Biotechnological applications: diagnostics, products

1) Domain Organisation and Function Collagen Integrin I II Fibrin Heparin I FN 7

1) Domain Organisation and Function Collagen Integrin I II Fibrin Heparin I FN 7 III FN 8 -10 FN 12 -14 IIIIII III Integrin III III I S, S Heparin Integrin - involved in cell adhesion, migration, matrix formation - binds to fibrin, integrin, heparin, collagens, gelatin, DNA - modular architecture consisting of type I, II and III repeats - FN 7 -10 binds integrins via the amino acid sequence RGD - FN 12 -14 binds heparin and integrin

Heparin binding Integrin binding

Heparin binding Integrin binding

Integrin binding Heparin binding

Integrin binding Heparin binding

GLOBAL INFORMATION FROM GENOMES MASS 2 D GE BIO-INFO SPEC

GLOBAL INFORMATION FROM GENOMES MASS 2 D GE BIO-INFO SPEC

PROTEOMICS - GLOBAL INFORMATION FROM GENOMES (m. RNA EXPRESSION STUDIES) - CLASSICAL REDUCTIONIST APPROACHES

PROTEOMICS - GLOBAL INFORMATION FROM GENOMES (m. RNA EXPRESSION STUDIES) - CLASSICAL REDUCTIONIST APPROACHES

BIOCHEMICAL REDUCTIONIST APPROACHES # aa, mol. wt. , p. I, extinction coeff. Glycosylation Signal

BIOCHEMICAL REDUCTIONIST APPROACHES # aa, mol. wt. , p. I, extinction coeff. Glycosylation Signal sequence Transmembrane segments Modifications (> 200) Protease cleavage sites Secondary structure prediction Function Fold, family, homologues 3 D structure Mutagenesis data Higher order complexes Expression Strategy Purification Strategy

P 16893 N C SS A-domain TM/CYT 200 aa TRM RGD Proline-rich region

P 16893 N C SS A-domain TM/CYT 200 aa TRM RGD Proline-rich region

Protein sequences alignment and protein modeling Protein sequencesProtein sequences alignment and protein modeling Protein sequences
PROTEIN OUTLINE Protein Definition Protein structure Protein FunctionPROTEIN OUTLINE Protein Definition Protein structure Protein Function
Protein Chemistry Basics Protein function Protein structure PrimaryProtein Chemistry Basics Protein function Protein structure Primary
Protein Basics Protein function Protein structure Primary AminoProtein Basics Protein function Protein structure Primary Amino
Protein Structure Primary Structure The primary structure isProtein Structure Primary Structure The primary structure is
Protein sequencing Determining protein sequences Why the proteinProtein sequencing Determining protein sequences Why the protein
Protein structures Protein Structure Why protein structure TheProtein structures Protein Structure Why protein structure The
Protein structure determination prediction Tertiary protein structure proteinProtein structure determination prediction Tertiary protein structure protein
Protein Simple Protein Conjugated Protein Derivative Protein SpecialProtein Simple Protein Conjugated Protein Derivative Protein Special
Protein Yaps Analizi Protein aileleri Protein lokalizasyonu proteinProtein Yaps Analizi Protein aileleri Protein lokalizasyonu protein
Protein Stability Protein Folding Protein Stability Protein stabilityProtein Stability Protein Folding Protein Stability Protein stability
Protein structure Four levels of protein structure PrimaryProtein structure Four levels of protein structure Primary
Maths Unit 10 Sequences Picture sequences Sequences canMaths Unit 10 Sequences Picture sequences Sequences can
Investigating Sequences and Series Arithmetic Sequences Arithmetic SequencesInvestigating Sequences and Series Arithmetic Sequences Arithmetic Sequences
Sequences Notes Day 1 Arithmetic Sequences Sequences thatSequences Notes Day 1 Arithmetic Sequences Sequences that
Investigating Sequences and Series Arithmetic Sequences Arithmetic SequencesInvestigating Sequences and Series Arithmetic Sequences Arithmetic Sequences
Geometric Sequences and Series Arithmetic Sequences Geometric SequencesGeometric Sequences and Series Arithmetic Sequences Geometric Sequences
Arithmetic Sequences Series Geometric Sequences Series Infinite SequencesArithmetic Sequences Series Geometric Sequences Series Infinite Sequences
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Arithmetic Sequences and Geometric Sequences Arithmetic Sequences AnArithmetic Sequences and Geometric Sequences Arithmetic Sequences An
Do TS Genes From Transcribed Sequences to GenesDo TS Genes From Transcribed Sequences to Genes
Genetics is the study of genes Genes sequencesGenetics is the study of genes Genes sequences
Genetics is the study of genes Genes sequencesGenetics is the study of genes Genes sequences
Genetics is the study of genes Genes sequencesGenetics is the study of genes Genes sequences