DIFFERENCES IN SCORE SCREENING PARAMETERS BETWEEN MALES AND
DIFFERENCES IN SCORE SCREENING PARAMETERS BETWEEN MALES AND FEMALES IN LATVIA Līva Mača 1, Cindy Heaster 1, Līga Esta 1, Sandra Gintere 2 Taisija Žeņiļenko 3 1 Rīga Stradiņš University Family Medicine Resident 2 Rīga Stradiņš University Health Center 3 Rīga Stradiņš University Faculty of Medicine Introduction and aim of the project Step 1: base SCORE calculation According to World Health organisation, Cardiovascular diseases are the leading cause of death globally, taking about 16’ 000 lives in Latvia annually 4, 5. Systematic Coronary Risk Evaluation (SCORE) system has been developed in order to assess the risk of it in the next 10 years. As at any given age, this risk is lower for women than men, the author wanted to compare the SCORE screening parameters between males and females. 4 Cardiovascular diseases (CVDs), World Health available on: https: //goo. gl/AYQx. Ny PAPER ID 23113 Anamnesis (complaints, family history, smoking status) Blood pressure, body mass index (weight, height), waist measurement Heart and carotid artery auscultation Total cholesterol and glucose analysis Step 2: SCORE adjustment Organisation, If total cholesterol > 7 mmol/l SCORE 10% If positive family history SCORE 10% If pathology on heart or carotid auscultation Echo If fasting glucose >6, 1 mmol/l repeat glucose + Hb. A 1 c Statistical data on mortality, National center of disease prophylaxis and control, available on: https: //goo. gl/Zy. SEb. F 5 Material and methods Patients in target age groups (40, 45 , 50 , 55 , 60, 65) were selected and SCORE protocol issued by health ministry was used to determine the cardiovascular disease risk. The data collected has been analyzed using IBM SPSS Statistics 23 (Kolmogorov-Smirnov Test (K), Mann-Whitney U (M), Pearson Chi-Square (C), Fisher’s exact test (F), and p<0. 05 was considered as statistically significant). Step 3: further investigation if SCORE 1% HDLP, LDLP, triglicerydes, creatinine levels, glomerular filtration rate (ALAT and CPK if statin therapy), EKG Echo. KG if pathology on auscultation, specific changes on EKG, arterial hypertension SCORE 3 -4% Brachiocephal artery US SCORE 10% Veloergometry Results Gender distribution in SCORE risk groups 11 10 9 This is an ongoing study. 22 males and 31 females have been included in this study. There were no differences in age distribution (K, p=0, 991) and smoking status (C, p=0, 086) for both sexes. Statistically significant difference was found for systolic blood pressure (M, p=0, 032) with mean of 128, 32 (SD=18, 82) mm. Hg for women and 141, 29 (SD=22, 38) mm. Hg for men. In this study body mass index (M, p=0, 313), waist circumference (M, p=0, 055), total cholesterol (M, p=0, 732) and fasting glucose levels (M, p=0, 493) did not differ between genders. 8 7 6 5 4 3 2 1 0 <1% <1 -2% 3 -4% Male 5 -9% >10% Female Systolic blood Diastolic blood Body mass pressure index (mm. Hg) (kg/m 2) Men Women 141, 29 128, 32 p = 0, 032 91, 81 80, 16 28, 77 27, 11 Although statistically significant difference was found in overall SCORE results (M, p=0, 001) with lower risk for female subjects (1, 37% (SD=1, 75%) versus 4, 63% (SD=5, 28%)), only the low risk group showed difference in gender distribution (8 women versus 0 men; F, p=0, 015). Waist circumference (cm) Total cholesterol (mmol/L) Glucose (mmol/L) 97 89, 39 5, 57 5, 42 5, 23 Overall SCORE (%) 4, 6 1, 37 p = 0, 001 Conclusions SCORE screening includes the assessment of such parameters as age, systolic blood pressure, total cholesterol and fasting glucose levels, as well as body mass index, waist circumference and smoking status. In this study differences between the sexes were found only for systolic blood pressure and total SCORE result with lower values for female subjects in both parameters.
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