Diagnosis of celiac disease in France daily practice

Diagnosis of celiac disease in France: daily practice of the prescriptions A French « EASI » Group Study Claire CHUPIN, Georges CHYDERIOTIS, Emmanuel CLAUDEL, Nicole FABIEN, Pr Alain LACHAUX, Lucile MUSSET, Nils-Olivier OLSSON, Bach. Nga PHAM Initiated and supported by

Goals of the Study • Optimizing communication between clinicians and laboratory specialists • Picture of the clinicians daily practice in celiac patients diagnosis • Informing the clinicians of the testing algorithm in celiac disease according to French official guidelines from the Haute Autorité de Santé “HAS” Initiated and supported by

Questionnaire (1) 1. How many celiac patients do you follow? Children (<18 years): Adults (>18 years): 2. 0 0 1 à 10 11 à 20 + de 20 11 à 20 + de 20 On which basis do you suspect a celiac disease? In a child <2 years: ………………………………………. . . In a child between 2 and 18 years: ……………………………………. . In an adult : …………………………………………… 3. In how many patients do you suspect a celiac disease per year? Children (<18 years): Adults (>18 years): 4. 0 0 1 à 10 11 à 20 + de 20 When there is a suspicion of celiac disease: You prescribe a biopsy You prescribe biological analyses You prescribe a biopsy and biological analyses simultaneously You prescribe a biopsy only after receiving the biological analyses results You prescribe biological analyses only after receiving the biopsy result You refer your patient to another clinician: which specialty : ………………. . . Initiated and supported by

Questionnaire (2) 5. If among the biological analyses, you prescribe a serology, which one(s) do you prescribe for celiac screening? Biological analyses Always Sometimes Never Doesn’t know this test Anti-transglutaminase Ig. A Antibodies Anti-transglutaminase Ig. G Antibodies Anti-gliadin Ig. A Antibodies Anti-gliadin Ig. G Antibodies Anti-endomysium Ig. A Antibodies Anti-endomysium Ig. G Antibodies Anti-reticulin Ig. A Antibodies Total Ig. A assay Initiated and supported by

• Questionnaire sent to : – 1 866 Gastroenterologists answers – 1 510 Pediatricians answers – 2 155 General practitioners answers 12% of 15% of 12% of Initiated and supported by

Diagnosis of celiac disease (1) General Practitioners Pediatricians Gastroenterologists Initiated and supported by

Diagnosis of celiac disease (2) Initiated and supported by

Follow up To all respondents * Sending of an EASI guide for celiac disease : Usefulness of Autoantibodies in the Diagnosis and Follow-up * Link to the French official recommandation website : www. has-sante. fr *http: //www. has-sante. fr/portail/upload/docs/application/pdf/fiche_buts_maladie_coeliaque. pdf *http: //www. has-sante. fr/portail/jcms/c_493810/recherche-dautoanticorps-diagnostic-de-la-maladie-coeliaque-et-suivi-delobservance-du-regime-sans-gluten Initiated and supported by