Delirium Detection Eric Mauri Michael Marquis Matthew Kasztejna

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Delirium Detection Eric Mauri Michael Marquis Matthew Kasztejna Advised by: Dr. Wes Ely

Delirium Detection Eric Mauri Michael Marquis Matthew Kasztejna Advised by: Dr. Wes Ely

Delirium Overview • • Brain’s form of organ dysfunction Impaired cognitive functioning Develops in

Delirium Overview • • Brain’s form of organ dysfunction Impaired cognitive functioning Develops in over 80% of ICU patients Direct consequence of medical conditions, medication, toxin exposure, or a combination of all of these.

Delirium Demographics • Occurs in 15 -60% of general patients and most frequent complication

Delirium Demographics • Occurs in 15 -60% of general patients and most frequent complication of hospitalization in older patients • Complicates 2 -3 million people yearly. • Involves over 17. 5 million inpatient days. • Over $4 billion in Medicare expenditures. • Development of delirium selected as one of the top three most important areas for quality of care improvement in older adults.

How is it detected? • Arousal Assessment – Ramsey Scale and Glasgow Coma Scale

How is it detected? • Arousal Assessment – Ramsey Scale and Glasgow Coma Scale • Attention Assessment – Confusion Assessment Method (CAM) • • Acute onset of mental changes Inattention Disorganized thinking Alertness

Project Objectives • Develop system that can continuously measure delirium in ICU patients –

Project Objectives • Develop system that can continuously measure delirium in ICU patients – Device must be small, cost-effective, comfortable, and practical – Real-Time measurements, data storage, and analysis of information (software)

Current Work • Researching companies for sleep detection systems on the market. • Researching

Current Work • Researching companies for sleep detection systems on the market. • Researching body signals indicating sleep status. • Early design requirements as dictated by ICU requirements.

Future Work • Review and evaluate preliminary findings. • Set a meeting with neurology

Future Work • Review and evaluate preliminary findings. • Set a meeting with neurology specialist Dr. Abhou-Kahalil at VUMC. • Speak with sleep specialist Atul Malhotra at Harvard to review and evaluate the device.