Definition of bulky disease in early stage Hodgkin

Definition of bulky disease in early stage Hodgkin lymphoma in computed tomography era: prognostic significance of measurements in the coronal and transverse planes by Anita Kumar, Irene A. Burger, Zhigang Zhang, Esther N. Drill, Jocelyn C. Migliacci, Andrea Ng, Ann La. Casce, Darci Wall, Thomas E. Witzig, Kay Ristow, Joachim Yahalom, Craig H. Moskowitz, and Andrew D. Zelenetz haematol Volume 101(10): 1237 -1243 September 30, 2016 © 2016 by Ferrata Storti Foundation

Representative images of the longest diameters measured using calipers of a right cervical mass in (A) transverse plane, 2. 6 cm and (B) coronal plane, 12. 1 cm. Anita Kumar et al. Haematologica 2016; 101: 1237 -1243 © 2016 by Ferrata Storti Foundation

Patient’s characteristics of early stage Hodgkin lymphoma, n=185. Anita Kumar et al. Haematologica 2016;

Correlation between maximal transverse and coronal measurements with lines for the 7 cm maximal transverse and coronal cut-offs for disease bulk. Anita Kumar et al. Haematologica 2016; 101: 1237 -1243 © 2016 by Ferrata Storti Foundation

Relapse-free survival (RFS) at four years for bulky disease subgroups defined as more than 7 cm in transverse or coronal plane. Anita Kumar et al. Haematologica 2016; 101: 1237 -1243 © 2016 by Ferrata Storti Foundation

Relapse-free survival (RFS) by presence of bulky disease. Anita Kumar et al. Haematologica 2016;

Relapse-free survival by presence of bulky disease (transverse or coronal max, diameter > 7 cm) and treatment [chemotherapy alone (Chemo) vs. combined modality therapy (CMT)]. Anita Kumar et al. Haematologica 2016; 101: 1237 -1243 © 2016 by Ferrata Storti Foundation

Relapse-free survival by presence of bulky disease (transverse or coronal max, diameter > 7 cm) in validation cohort patients (n=38) treated with chemotherapy alone. Anita Kumar et al. Haematologica 2016; 101: 1237 -1243 © 2016 by Ferrata Storti Foundation