Cyclospora cayetanensis Infectious Agent Symptoms Protozoan Disease caused

Cyclospora cayetanensis Infectious Agent Symptoms • Protozoan • Disease caused = cyclosporiasis • Must be sporulated in the soil • Cyclical watery diarrhea from wks – months with fatigue, weight loss, anemia, nausea, malaise, and abdominal cramping • Self-limiting up to 9 wks in adults Epidemiology & Risk Groups Diagnosis • Increasing incidence in the US especially in summer months • Affects immunocompromised patients more severely • Erythema of the distal duodenum • Tissue biopsy contains the sexual forms, and/or oocysts • Stool samples with oocysts • Oocysts might stain positive with acid-fast Transmission Treatment • Food/water borne • Human-human transmission doesn’t occur due to the necessary sporulation step in the soil • Trimethoprimsulfamethoxazole (TMPSMZ) • Prevent dehydration Pathogenesis 1 -11 days 2 – 9 wks Incubation period - Ingestion of the sporulated oocysts - Prodromal symptoms are flulike Primary Symptoms - Oocysts excyst in small bowel a and invade epithelial cells - Asexual and sexual reproduction occurs - Unsporulated oocyst are excreted in feces - Oocysts must spend time in soil to become sporulated and infectious These icons were found on the Noun Project: Microscope: Created by Dumitriu Robert, Globe by Tinashe Mugayi, Mosquito: Created by Edward Boatman, Bacteria: Created by Maxim Kulikov, Person: Created by Hayashi Fumihiro, Disease: Created by nayeli zimmerman, Rare Disease: Created by Heads. Of. Birds, Syringe and Medicine: Created by Sergey Demushkin