Comparison on Proton Therapy Institutional Data Paige Summers

Comparison on Proton Therapy Institutional Data Paige Summers, MS This project is supported by the Federal Share of program income earned by Massachusetts General Hospital on C 06 CA 059267, Proton Therapy Research and Treatment Center and by grants CA 10953 and CA 81647 (NCI, DHHS).

Proton Centers Reviewed: Fast Facts • 8 US proton centers reviewed (one twice) • Synchrotrons and cyclotrons • Scattered & uniform scanning • Fixed, incline and rotating gantry beam lines • Xi. O, Eclipse and Odyssey planning systems • Philips, Siemens, and GE CT scanners • Treating pediatric and adult patients

Output Results • Criteria: ± 5% • Dosimetry system intercomparison performed with Institution, RPC ion chambers and electrometers • Measured for reference field • Patient field comparisons made with ion chambers and ion chamber arrays (cross calibrated same day) Institution Output RPC/Inst. A 0. 99 - 1. 02 B 1. 00 - 1. 02 C 0. 95 - 1. 02 D 0. 96 - 1. 02 E 0. 97 - 1. 00 F 0. 95 - 1. 01 G 0. 98 - 1. 01 H 0. 97 - 1. 02 I 0. 96 - 1. 00

CT Scanner Recommendations Institution RLSP RPC/Inst. A 0. 88 - 1. 01 B 0. 99 - 1. 04 C 0. 79 - 1. 02 D 1. 00 - 1. 04 E 0. 96 - 1. 08 F 0. 97 - 1. 23 G 0. 97 - 1. 13 H 0. 96 - 1. 17 I 0. 79 - 1. 02

Phantom Results Institution Phantom: RPC/Inst DTA [mm] A 0. 95 – 0. 96 1– 3 B 0. 96 – 0. 97 1– 4 C 0. 95 – 0. 97 0– 2 D 0. 96 – 0. 97 1– 4 E 0. 94 0– 4 F 0. 95 – 0. 96 0– 3 G 0. 94 – 0. 96 1– 3 H In progress - I In progress - • RPC/Inst ratio measured using TLD (± 7%) • DTA measured using Gafchromic film (± 4 mm)

Phantom Results

RPC Proton Site Visits • After visits, RPC generates comprehensive site visit report – sent to institution with recommendations RPC Recommendations Treatment On Board CTN-RSP CT Scaling Planning Imaging 8 1 2 3 QA Total (9 visits) 39 53 • QA recs: range uniformity, output, lateral penumbra, distal penumbra, QA procedures, equipment

Proton TLD Results

Questions? ? ?

Other RPC Proton Activities • NIST/proton ion chamber intercomparison Cylindrical chambers • 9 institutions & NIST participated • Calorimetry experiment planned 6/2012 • 56% of calcs <1% diff Parallel plate chambers TRS-398 • 94% of calcs <2% diff • Two meetings with AAPM proton advisory group • Focused scope of measurements, rewrote proton guidelines for clinical trials

Pelvis Phantom Results Lung Phantom Results