COMPARING IPRO WITH LIBRE FOR SENSOR ACCURACY AND

COMPARING IPRO WITH LIBRE FOR SENSOR ACCURACY AND USER FRIENDLINESS Jothydev Kesavadev , Arun Shankar, Pradeep Sadasivan Pillai, Ashwin David, Geethu Sanal, Remya Iyer, Gopika Krishnan, Sunitha Jothydev's Diabetes Research Centre, Thiruvanathapuram, India. www. research. jothydev. com jothydev@gmail. com BACKGROUND Continuous glucose monitoring (CGM) systems use a tiny sensor inserted under the skin to check glucose levels in interstitial fluid. The sensor stays in place for several days to 2 weeks. CGM can be used to supplement blood glucose meter readings for more informed treatment decisions and improved glycemic control. The Free. Style Libre Pro Flash glucose monitoring system is a new deice which has several features that distinguish it from existing sensor technology. The wired enzyme sensor is calibrated in the factory and therefore requires no user calibration during 14 days of wear to receive a glucose readings with a 15 -min frequency. This feature differs from existing sensors, which require multiple finger stick blood glucose measurements over the life of the sensor for calibration. The blood glucose readings on the built-in meter are independent of, and do not influence, sensor readings. . AIM This study examined the ability of this new device, Libre Pro, to detect glucose levels compared with a currently available device, i. Pro 2, in healthy individuals and diabetes patients. RESULTS The difference in the glucose values of the shown graph (Fig. 1) ), of Libre Pro from i. Pro 2 was -15. 8 mg/d. L (SD 49. 2, mean absolute percentage error 28. 5%). A concordance analysis showed that the concordance correlation coefficient 0. 15. METHODS Two each of type 1 diabetes, type 2 diabetes, gestational diabetes mellitus, prediabetes and healthy individuals participated in the study. Both sensors were initiated simultaneously in the study participant. Blood glucose values were also monitored with calibrated glucose meter. Data from day 2 to day 6 were analyzed. Statistical methods, including concordance analysis, were used to analyze results. CONCLUSIONS The overall glycemic pattern generated by the two devices were similar. The major advantages of Libre Pro sensor were that it precludes finger pricks for calibration, its smaller size, simplified insertion and data downloading techniques and 14 days of sensor life. Mean absolute percentage error being 28. 5%, randomized controlled trials in patients with rapidly fluctuating blood glucose, are warranted to better prove accuracy and reliability of this new sensor. REFERENCES Bailey T, Bode BW, Christiansen MP, Klaff LJ, Alva S. Performance and Usability of a Factory-Calibrated Flash Glucose Monitoring System. Diabetes Technol Ther. 2015 Nov; 17(11): 787 -94.