Community Curation of Gene Descriptions Ranjana Kishore Worm

Community Curation of Gene Descriptions Ranjana Kishore Worm. Base@Caltech Pasadena, California

Gene concise descriptions are snapshots of gene function Key data: orthology, process, molecular function, tissue and subcellular expression data (all from published papers).

Help us with writing and updating gene descriptions Writing and updating gene descriptions are labor-intensive and time-consuming Use our community curation system and participate in writing gene descriptions!

How can you help with Worm. Base Gene descriptions? -Write a new gene description (eg. for a newly published* gene). -Update an old gene description with new published* data. -Refine/Update our automated descriptions written by scripts (based on orthology and gene ontology (GO) data previously curated in Worm. Base). Example of an automated description: “hmg-1. 2 is an ortholog of human HMGB 2 (high mobility group box 2), HMGB 1 (high mobility group box 1), HMGB 3 (high mobility group box 3) and HMGB 4 (high mobility group box 4); hmg-1. 2 is involved in cell fate specification, Wnt signaling pathway, vulval development, positive regulation of transcription from RNA polymerase II promoter and hermaphrodite genitalia development; hmg-1. 2 exhibits transcription regulatory region DNA binding activity; hmg-1. 2 is localized to the nucleus”. *No meeting abstracts or Worm Breeder Gazette articles please

Using the Gene Description Submission Form Step 1: Enter your name and e-mail address Follow the links from here to this form

Step 2: Pick a gene and write a new description (if none) or edit the existing gene description

Step 3: Enter references for the gene description and then Preview and Submit You just contributed a gene description!

Acknowledgements Juancarlos Chan (Developing the form and software) James Done (Automated descriptions project) Worm. Base people at Caltech (For everything else!)