Common Spirit Health Antigen Testing and Reference Laboratory

Common. Spirit Health Antigen Testing and Reference Laboratory Opening Karen Smith, MBA, MT (ASCP) System Vice President, Laboratory Services

Topics Antigen Testing Guidelines Molecular Testing 4 -Plex Common. Spirit Reference Lab

Common. Spirit Health Guidelines for the use of SARS-COV-2 Antigen Tests

SARS-COV-2 Antigen Testing Detects the protein on the virus versus the RNA used in molecular/PCR testing Not as sensitive as molecular/PCR testing Particularly helpful if testing is performed in the early stages of the infection when viral load is generally highest Limited data to guide use as a screening assessment on asymptomatic patients

Guidelines in Brief Ambulatory ONLY Use for symptomatic patients only NOT INTENDED FOR SCREENING All negatives confirmed by ONE of the following • Reflex to molecular/PCR • Repeat Antigen test at 24 AND 48 hours

1. Antigen testing should be considered only for symptomatic patients in the ambulatory setting, or patients with exposure to a confirmed case of COVID-19 a. NAAT/molecular tests are generally more appropriate for ED and acute care inpatients b. NAAT/molecular tests are generally more appropriate for asymptomatic patients 2. Antigen testing of symptomatic patients in the ambulatory setting is particularly useful when NAAT/molecular testing: a. Has a high positivity rate in the community (e. g. , greater than 10 percent) b. Is not available or has an unacceptably long turnaround time 3. If the test result of a symptomatic patient in the ambulatory setting is positive, then it may be interpreted as presumptive of an acute infection 4. If the test result of a symptomatic patient in the ambulatory setting is negative, then the patient should isolate at home pending elucidation of infection status if symptoms are mild, or present to an ED if symptoms are severe a. The infection status of the patient should be clarified by either i. NAAT/molecular test with the patient remaining in isolation pending the result ii. Repeat antigen test in 24 hours and if negative, repeat again in another 24 hours, with the patient remaining in isolation pending the results b. If the NAAT/molecular test or all three antigen tests (at 0, 24 and 48 hours) are negative, then the patient may be presumed to not be infected and may be released from isolation

See CDC Guidelines for Antigen Testing in Nursing Homes https: //www. cdc. gov/coronavirus/2019 -ncov/hcp/nursing-homes-testing. html

Molecular Testing During Flu Season 4 -Plex Test (Flu A/B, RSV, COVID)

Hospital Testing In-patients Symptomatic Employees ED Same-day Surgeries Testing Platforms Cepheid BD Max Abbott Panther

Off-Site Testing Common. Spirit Reference Lab-Scottsdale AZ Open for testing September 8 th Capacity for 10, 000 tests/day

Go-Live October 12 th

DATE TBD Hospital Name Arroyo Grande Community Hosp French Hospital Medical Center Marian Medical Center St. John's Pleasant Valley Hosp St. John's Regional Medical Ctr Bakersfield Memorial Hospital Mark Twain Medical Center Mercy Hospital Bakersfield - Truxton Mercy Medical Center Merced Mercy Hospital Southwest - Bakersfield St. Joseph's Med Ctr Stockton/HCCL St. Bernardine Medical Center Community Hosp San Bernardino California Hospital Med Ctr Glendale Memorial Hosp & Hc Northridge Hosp Med Ctr Roscoe St. Mary Medical Center (LB) State CA CA CA CA CA Division Central Coast Central Coast Central California Central California Southwest Southwest 13

DATE TBD Hospital Name St. Alexius Health - Dickinson Med. Ctr. St. Alexius Health - Williston Med. Ctr. St. Alexius Health - Devils Lake Hosp St. Alexius Health - Carrington Med. Ctr. CHI Lisbon Health CHI Mercy Health Valley City Northern Plains Lab (NPL) Mercy. One Centerville Family Med. Mercy. One West Des. Moines Med. Ctr. Mercy. One Newton St. Vincent - Conway St. Joseph - Mount Sterling Trinity Hospital - Twin City State ND ND IA IA IA AR KY OH Division Fargo Fargo Midwest Southeast 14

Planning Stages Ambulatory Home Health Employee Commercial

If you have questions, contact Karen Smith. Thank you. 16