Combined CD 8 and CD 4 adenovirus hexonspecific

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Combined CD 8+ and CD 4+ adenovirus hexon-specific T cells associated with viral clearance

Combined CD 8+ and CD 4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection by Maarten L. Zandvliet, J. H. Frederik Falkenburg, Ellis van Liempt, Louise A. Veltrop-Duits, Arjan C. Lankester, Jayant S. Kalpoe, Michel G. D. Kester, Dirk M. van der Steen, Maarten J. van Tol, Roel Willemze, Henk-Jan Guchelaar, Marco W. Schilham, and Pauline Meij haematol Volume 95(11): 1943 -1951 October 31, 2010 © 2010 by Ferrata Storti Foundation

HAd. V hexon-specific T cells in healthy donors. Maarten L. Zandvliet et al. Haematologica

HAd. V hexon-specific T cells in healthy donors. Maarten L. Zandvliet et al. Haematologica 2010; 95: 19431951 © 2010 by Ferrata Storti Foundation

HAd. V-specific T-cell responses in allogeneic SCT recipients. Maarten L. Zandvliet et al. Haematologica

HAd. V-specific T-cell responses in allogeneic SCT recipients. Maarten L. Zandvliet et al. Haematologica 2010; 95: 19431951 © 2010 by Ferrata Storti Foundation

Detailed analysis of HAd. V-specific T-cell responses in allogeneic SCT recipients. Maarten L. Zandvliet

Detailed analysis of HAd. V-specific T-cell responses in allogeneic SCT recipients. Maarten L. Zandvliet et al. Haematologica 2010; 95: 19431951 © 2010 by Ferrata Storti Foundation

Example of a HAd. V-specific T-cell line containing CD 8+ and CD 4+ T

Example of a HAd. V-specific T-cell line containing CD 8+ and CD 4+ T cells with high specificity for HAd. V hexon. Maarten L. Zandvliet et al. Haematologica 2010; 95: 19431951 © 2010 by Ferrata Storti Foundation

Generation of T-cell lines containing CD 8+ and CD 4+ T cells with high

Generation of T-cell lines containing CD 8+ and CD 4+ T cells with high specificity for HAd. V hexon derived from six healthy adult donors. Maarten L. Zandvliet et al. Haematologica 2010; 95: 19431951 © 2010 by Ferrata Storti Foundation