Combination Of Antioxidant And Ovulation Induction Drugs And

Combination Of Antioxidant And Ovulation Induction Drugs And Evaluation Of Pregnancy Rate In Infertile Women Jahromi Rasekh(M. D)1, Maalhagh Mehrnoosh(M. S)2 Alipour Farzaneh(M. S) 2 , Sobhanian Saeed(M. Sc)3, Pad Neda(B. Sc)4 , n. • Medical student, Jahrom University of medical sciences, Jahrom, Iran. • B. Sc in Midwifery, Dr. Rasekh Clinic, Jahrom University of medical sciences, Jahrom, Iran. • Email; Drrasekh@yahoo. com Ovarian hyperstimulation syndrome (OHSS) is an I Objectives Many studies reported that antioxidants such as vitamin E, vitamin C help to scavenge the oxygen radicals throughout the female reproductive tract that might improve the infertility treatment. The aim of this research is adjusted a regimen that is a combination of antioxidant and Ovulation induction drugs and evaluation of pregnancy rate. . . Methods : this is a clinical study which was done on 202 infertile women Results At the end of the study 25. 7% of patients treated with this regimen were pregnant. 44. 6% of follicular sizes were more than 18 mm. 68. 7% of patients had high quality of endometrium(triple layer & lucid). 71. 6% of endometrial thickness were more than 8 mm. Conclusions Based on the results of this study, this regimen can improve the endometrial quality and thickness which are required for successful implantation of fetus in uterus. Also this regimen had acceptable effects on follicular size which is one of the basic steps in success of ovulation induction. Pregnancy was occurred in 1 woman between 4 infertile women. For evaluations of the results, this study must be done on numerous of infertile patients to achieve meaningful results. Another important factor; availability of drugs, low cost. . Key words: Infertility, antioxidants, letrozole, Tamoxifen, estrogen, that referred to Dr. Rasekh clinic in Jahrom city during 24 months. Results are reported as number and percentage and the Chisquare test. All these patients were treated with regimen include letrozole+ tamoxifen +estrogen + vitamin E. Most of the women in this study was in range of 20 -30 years old(63. 4%). 24. 8% of patients were case of PCO syndrome. Frequency of pregnancy was reported based on endometrial quality, endometrial thickness and follicular size. Data was analyzed by SPSS 21. References