Cloning Animals GCSE Module 14 Biotechnology Lesson 10

Cloning Animals GCSE Module 14 Biotechnology Lesson 10 a

Lesson objectives: • You will understand the stages in the production of a cloned mammal • You will be able to understand the social and ethical concerns of cloning mammals

How Dolly was made? To produce a cloned mammal is extremely difficult. A diploid nucleus from a mature cell is inserted into an enucleated egg cell. The cell is then stimulated and the diploid nucleus divides by mitosis. Once the egg cell has reached the embryo stage it is inserted into a surrogate mother to develop into a new individual. The majority of embryos will fail.

Activities: 1. Produce a flow-chart of the stages in the production of a cloned mammal. Use the Roslin Institute website : the sheep 2. Then use either the Roslin web-site or BBC News | SCI/TECH | Pig cloning race hots up to find out about the medical and ethical issues raised of using cloned body parts from humans and animals for transplant surgery. 3 Produce a 1 page text document or simple notes for discussion next lesson with the class.

Plenary: Take 15 minutes to discuss, with a partner, the issues raised by the use of cloned body parts from humans and animals for transplant surgery and then decide whether you are for or against this therapy being used. Add any extra thoughts to your prepared notes. Put forward your views during the class discussion but always remember to allow others to speak and voice their opinions – even if you disagree.