Clinical Research Awareness Campaign For Member Company Use

Clinical Research Awareness Campaign For Member Company Use Only Last Update: June 2020 (v 3)

What challenges do sponsors face? It is estimated that over 58 million people are needed to fill the demand of enrolling studies found on Clinical. Trials. gov 1 That is about 1 in 6 people in the U. S. Meanwhile, 15 -20% of sites never enroll a single patient 2 and actual enrollment timelines are typically double that of planned timelines 3 1. Courtesy of Lilly Trials. http: //enrollment-demand. lillycoi. com/ 2. University of North Carolina at Chapel Hill, Office of Clinical Trials Newsletter. Budgeting at the Investigator Site. July / August 2006. 3. Getz, Ken at Tufts Center for the Study of Drug Development. The Cost of Clinical Trial Delays. January 2015. Copyright © 2017 Trans. Celerate Bio. Pharma Inc. , All rights reserved. * Confidential - NOT FOR DISTRIBUTION * 2

What is “One Person Closer”? “One Person Closer” is designed to put a human face on research and development by sharing the personal stories of researchers, health care professionals and patients who have contributed to clinical research and the development of medical breakthroughs. The digital initiative aims to show doctors, nurses and other health care professionals that they can help facilitate research that advances science and that may benefit their patients. Copyright © 2017 Trans. Celerate Bio. Pharma Inc. , All rights reserved. Awareness Encourage informed conversations about clinical trials between patients and their HCPs * Confidential - NOT FOR DISTRIBUTION * 3

Clinical Research Awareness Campaign Launch Date: February 6 Branding • • Venues & Platforms • • Multimedia press release STAT-sponsored campaign page Tweet chat Figure 1 live chat Online influencers Member co. activity • • • Branding Panelist & sponsor mentions Facebook Live fireside chat Conf. organizer promotion • • Media: Interviews / bylines / Q&A’s HCP-attended conference speaking opportunities Continued member company engagement Continued online influencer activation (HCPs and advocates) The future of medicine is up to you. Get #1 Person. Closer #4 Your. Patient Find new possibilities #4 Your. Patient. Every participant in a #clinicaltrial brings us #1 Person. Closer to developing new medicine. Shareable Content Branding Video posts Call to action posts Data image posts #Gratitude. Doug Jensen, who suffers from Chronic Myeloid Leukemia, talks about his experience as a #clinicaltrial participant. We need millions more like him – please refer your patients to clinical trials. #One. Person. Closer Webinars will be held in February for member company representatives and external organizations wishing to become involved in the campaign. A toolkit of content, guidelines, and best practices will also be available Copyright © 2017 Trans. Celerate Bio. Pharma Inc. , All rights reserved. * Confidential - NOT FOR DISTRIBUTION * 4

Multimedia Press Release Influencers STAT Article and Petition • Kick’s off campaign • Will be shared with influencers and media outlets in advance • • • Article on Tom Marsilje, scientist and cancer patient • Fierce patient advocate and supporter of helping others navigate confusing world of cancer treatments and clinical trials • Nation. Builder petition to show support for Tom’s work and increased awareness of clinical trials 20 major influencers Over 100 media outlets 30+ Trans. Celerate relationships Member Companies Social Media Faces of the Campaign • Facebook and Twitter One Person Closer Page • Linked. In • Plan for posts throughout Feb/March to promote campaign, invite comment, a call to action and announce live events • • • SERMO 5 min poll to collect information on what is preventing physicians from discussing clinical trials with their patients Live Activities Copyright © 2017 Trans. Celerate Bio. Pharma Inc. , All rights reserved. 12 individuals (HCPs; researchers and patients) Shareable videos &portraits 3 composite videos Quotes All useable in social media posts • Webinars for Member Companies and external organizations to discuss the campaign and how to get involved • SCOPE: Facebook Fireside Chat and closing slide • Figure 1 Chat on Feb 20: HCP focused social media platform. Centers around why HCPs and patients are hesitant to participate in Clinical trials • Tweet Chat on Feb 21: Centers around why HCPs and patients are hesitant to participate in Clinical trials * Confidential - NOT FOR DISTRIBUTION * 5