Clinical phenotype and genetic associations in autosomal dominant

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Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer’s disease: a case series

Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer’s disease: a case series Dr Natalie S Ryan, MRCP, Jennifer M Nicholas, Ph. D, Philip S J Weston, MRCP, Yuying Liang, MRCP, Tammaryn Lashley, Ph. D, Rita Guerreiro, Ph. D, Gary Adamson, BSc, Janna Kenny, MRCP, Jon Beck, FRCPath, Lucia Chavez-Gutierrez, Ph. D, Prof Bart de Strooper, Ph. D, Prof Tamas Revesz, FRCPath, Prof Janice Holton, FRCPath, Prof Simon Mead, Ph. D, Prof Martin N Rossor, MD, Prof Nick C Fox, MD The Lancet Neurology Volume 15 Issue 13 Pages 1326 -1335 (December 2016) DOI: 10. 1016/S 1474 -4422(16)30193 -4 Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 1 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4)

Figure 1 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 2 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4)

Figure 2 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 3 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4)

Figure 3 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 4 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4)

Figure 4 The Lancet Neurology 2016 151326 -1335 DOI: (10. 1016/S 1474 -4422(16)30193 -4) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

single gene disorders Mendelian disorders autosomal dominant autosomalsingle gene disorders Mendelian disorders autosomal dominant autosomal
Mendelian Pedigree patterns Autosomal dominant Autosomal recessive XLinkedMendelian Pedigree patterns Autosomal dominant Autosomal recessive XLinked
Mendelian Pedigree patterns Autosomal dominant Autosomal recessive XLinkedMendelian Pedigree patterns Autosomal dominant Autosomal recessive XLinked
single gene disorders Mendelian disorders autosomal dominant autosomalsingle gene disorders Mendelian disorders autosomal dominant autosomal