Chemotrophy and Mitocondria Aerobic Respiration Cellular Respiration How
Chemotrophy and Mitocondria Aerobic Respiration
Cellular Respiration Ø How do cells make use of the potential energy present in chemical bonds of the nutrient molecules? Ø What is the role of NAD+ reactions? and FAD in these Ø How do cells that cannot make use of oxygen obtain energy?
Glycolysis Ø What happens during this process?
Fate of Pyruvate Ø In cells that cannot use oxygen, or when oxygen is not available, what happens to the pyruvate generated by glycolysis?
Fermentation Reactions Ø Why is fermentation to either lactate or ethanol important to the cell? Ø What is true about the end products with respect to energy?
Regulation of Glycolysis
Role of Mitocondria in Respiration
Mitocondrial Structure
Mitocondrial Structure Ø What do we know about the different components of a mitocondrion? Ø How does the size, shape and number vary?
Mitocondrial Function Ø Where in the mitocondria do various functions take place?
Mitocondrial Function Ø How is membrane structure intimately connected with mitocondrial function?
TCA or Krebs Cycle Ø Before this cycle can take place, pyruvate from glycolysis must be converted to acetyl Co. A. How and where does this take place?
Coenzyme A
TCA or Krebs Cycle
TCA or Krebs Cycle Ø Where is most of the energy from the Krebs cycle? Ø Why is this cycle central to metabolism?
TCA or Krebs Cycle Ø Besides glycolysis what other process fuels this cycle?
TCA or Krebs Cycle Ø What is the connection between protein degradation and the TCA cycle?
TCA or Krebs Cycle Ø How else does the TCA cycle contribute to the cell’s metabolism?
TCA or Krebs Cycle Ø How is the TCA cycle regulated?
Glyoxylate Cycle Ø What is the glyoxylate cycle and how is it used?
Electron Transport Ø What takes place during electron transport?
Electron Transport Ø What is meant by the reducing potential and how does this apply to the ets? Ø What are the different kinds of carriers in the ets?
Electron Transport
Reduction Potential Ø How do we determine the e- transfer potential of an ets component?
Reduction Potential Actual reduction potential El = Elo RT/n. F ln ox. form/red. form Ø ΔGol = n. FΔElo
Electron Transport System
Electron Transport System
Oxidative Phosphorylation Ø What is involved in this process? Ø How is electron transport coupled to ATP synthesis?
Oxidative Phosphorylation
Oxidative Phosphorylation Ø What regulates the rate of oxidative phosphorylation? Ø How much ATP is generated for each O 2 consumed?
Oxidative Phosphorylation Ø What evidence supports the chemiosmotic hypothesis?
ATP Synthesis Ø How did Racker show that membrane particles were involved in ATP synthesis?
ATP Synthesis Ø What are the components of Fo. F 1 ATP synthase?
ATP Synthesis
ATP Synthesis
Aerobic Respiration Ø What is maximum yield of ATP?
Glycerol Phosphate Shuttle
Other Transport Systems
- Slides: 38