Chem 108 Lab Week 17 Sign in Pick

Chem 108: Lab Week 17 • Sign in • Pick up papers & Lab Drawer Inventory Sheet & Tag for Lab combination lock • Sit @ your original Lab Drawer Station

Chem 108 Synthesis of Aspirin Weigh crude aspirin & calculate % yield. Turn in individual Report Form with partner’s name(s). Due Today Weigh Aspirin Calculate % Yield Report Form Due Today

Aspirin Uptake: In lieu of clinically testing your crude aspirin product, rank the following 4 possible routes of entry into the bloodstream from slowest to fastest. a) injection; b) ingestion; c) inhalation; d) snorting A) a<b<c<d B) c<a<d<b C) b<d<a<c D) d<b<c<a

Mass Calculations: grams (Salicylic Acid) grams (Aspirin) Moles Molar Mass Stoichiometry C 9 H 8 O 4 MW = 180. 15 grams (A) 6. 0 grams (SA) 1 mol A grams (SA) 1 mol SA (Molecular Weight SA) "Gatekeeper" C 7 H 6 O 3 MW = 138. 12 (Molecular Weight A) ? (A) 1 mol (A) 7. 8 g aspirin

Percent Yield In synthesis as in any experiment, it is very difficult and at most times impossible to be perfect. Therefore the actual yield (g) is measured and compared to theoretical calculated yield (g). This is the percent yield: % Yield = actual (g) / theoretical (g) x 100

FINAL EXAM WEDNESDAY, May 23 rd 10: 30 AM – 12: 30 PM Comprehensive Questions taken from today’s Lab & Selected Topics class materials; Remaining questions based on previous 3 Exams. 30 Multiple Choice (4 pts ea); 15 T/F (2 pts ea) plus matching & 8 problems; (200 pts TOTAL) 5 pages 2 -sided handwritten notes + Periodic Table

Anonymous End of Course Survey Available 16 -May to 23 -May End of course anonymous survey: Due 23 -May. Full Quiz Credit provided on completion. • Go to https: //salgsite. net/student • * Fill in your email address • * Enter the instrument number: • * Provide the instrument password: chem 108

Natural & Synthetic Polymers

Polymers

Polymers Macromolecules that are made from smaller molecules, “monomers” or “co-monomers”, which structurally repeat themselves. Monomer Polymer Ethylene Polyethylene Vinyl chloride Polyvinyl chloride Tetrafluoroethylene Teflon Amino Acids Proteins Nucleotides (Bases) DNA & RNA

Polyethylene: Polymerization

Polyethylene & Other “Plastic” Waste ~250 billion pounds produced annually, worldwide.

http: //chemconnections. org/general/chem 106/Tech%20 Prep/DNA-2016. html Chem 108: Class/ Lab Week 17 Natural Polymers At Home: Strawberry DNA Extraction Spooling Strawberry DNA @ home: https: //www. youtube. com/watch? v=67 KXatgo. NKs Banana DNA @ home: https: //www. youtube. com/watch? v=23 j. Sj-B 18 g. M Australian Banana DNA @ home: https: //www. youtube. com/watch? v=ew 9 -YGrgp. Wo (Substitute chilled rubbing alcohol)

DNA / Genetics / Proteins

1953

1953 DNA: Molecular Discovery X-Ray Crystal Structure http: //info. bio. cmu. edu/courses/03231/Prot. Struc. htm β-DNA: Rosalind Franklin 46 Å 12 base sequence http: //molvis. sdsc. edu/pdb/dna_b_form. pdb

1989 PCR: Polymerase Chain Reaction Kary Mullis, Cetus-Chiron-Roche, Emeryville Ken Myambo Cetus Research Associate https: //www. dnalc. org/resources/3 d/19 -polymerase-chain-reaction. html

1995 Genetic Fingerprinting 2018 Golden Gate Killer/ East Area Rapist http: //www. diablomag. com/Febr uary-2018/Chasing-Evil/ • Forensics • Paternity • Military-ID • Food • Wine • Anthropology • Medical Diagnosis • Genealogy • Cloning • Genomics: Human & Many Others OJ Simpson and the bloody glove.

Check in lab drawer Chem 108: Class/ Lab Week 17 1. 2. 3. 4. 5. 6. (Return loaned i-clickers) Check that you have everything on the inventory sheet: clean & not broken Go to stockroom to replace any missing or broken items. Replace the paper @ the bottom of the drawer with clean paper towel Take a tag, write the combination number on the tag & fasten to lock Write your name on the board. Dr. R. will check in order & sign off your inventory sheet Take the combination lock & signed sheet to the stockroom to be stamped