Chapter 59 Cephalosporins Mosby items and derived items

Chapter 59 Cephalosporins Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 1

Drug Overview Cephalosporins Ø Ø Ø Indications Ø Ø First generation Second generation Third generation First generation Second generation Allergy Resistance Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 2

Mechanism of Action Drug Action Spectrum of Activity Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 3

Mechanism of Action Spectrum of Activity (cont’d) Ø Ø Ø First generation Second generation Third generation Limitations of Effectiveness Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 4

Treatment Principles How to Monitor Patient Variables Ø Ø Ø Geriatrics Pediatrics Pregnancy Patient Education Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 5

cephalexin (Keflex) Contraindications Warnings Precautions Pharmacokinetics Adverse Effects Drug Interactions Overdosage Dosage and Administration Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 6

Other Drugs in Class First Generation Ø Ø cefadroxil (Duricef) cephadrine (Velosef) Second Generation Ø Ø Ø cefuroxime (Ceftin) cefprozil (Cefzil) Others Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 7