Chapter 58 Penicillins Mosby items and derived items

Chapter 58 Penicillins Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 1

Drug Overview Natural Penicillins Aminopenicillins Ø Penicillinase-Resistant Penicillins Ø Antistaphylococcal penicillins Carboxypenicillins Ø Second generation; activity against gram bacilli Third generation; antipseudomonal penicillin Ureidopenicillins Ø Fourth generation; antipseudomonal penicillin Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 2

Drug Overview Indications Allergy Resistance Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 3

Mechanism of Action Drug Action Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 4

Treatment Principles Spectrum of Activity Empirical Therapy Treatment Duration Activity Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 5

Treatment Principles How to Monitor Patient Variables Ø Ø Geriatrics Pediatrics Pregnancy and lactation Gender Patient Education Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 6

penicillin VK Contraindications Warnings Precautions Pharmacokinetics Adverse Effects Drug Interactions Overdosage Dosage and Administration Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 7

Other Drugs in Class Natural PCNs Ø Ø aminopenicillin Ø Ø Ø penicillin G penicillin V ampicillin amoxicillin/potassium clavulanate Penicillinase-Resistant Penicillins Mosby items and derived items © 2009, 2004 by Mosby, Inc. , an affiliate of Elsevier Inc. 8