Chapter 14 Chromosome 14 DNA Sequence Chromosome 14

Chapter 14: Chromosome 14 DNA Sequence Chromosome 14 Name of Gene PSEN 1 Name of Protein 87257 bp Precilin 1 transcription m. RNA Amino acid sequence 378 aa translation What does this protein make up or do? PSEN 1 is working incorrectly it mutations amyloid precursor protein and they can lead to Alzheimer's. n. When Condition/Disease Alzheimer's

Description of Alzheimer's Symptoms: 1. Memory loss that effects daily life. 2. Confusion with time or place. Characteristics 3. Memory loss Normal Vision As viewed by a person with glaucoma Pictures used with permission from URL: http: //www. nei. nih. gov/health/glaucoma_facts. asp

Description of Alzheimer's Who (cont. ) is affected? People over the age of 65 Studies have shown that women tend to be diagnosed with Alzheimer's then men do. Passed down through genes Head injury Outlook or quality of life No known cure yet Tends to get worse as you age Tend to need care as the disease gets worse. Researcher: AW

References http: //www. alzheimer-europe. org/Dementia/Alzheimer-sdisease/Main-characteristics-of-Alzheimer-sdisease? #fragment-1 http: //www. alz. org/alzheimers_disease_10_signs_of_alzhei mers. asp https: //www. google. com/#q=who%20 can%20 be%20 affecte d%20 by%20 alzheimer%27 s http: //ghr. nlm. nih. gov/gene/PABPN 1 http: //www. ncbi. nlm. nih. gov/gene? cmd=retrieve&dopt=full_r eport&list_uids=5663 http: //ghr. nlm. nih. gov/gene/PSEN 1