Chapter 13 Lesson 13 2 anemia Hemolytic anemia

  • Slides: 13
Download presentation
Chapter 13 Lesson 13. 2 anemia Hemolytic anemia sickle cell Hemochromatosis Hemophilia leukemia Mononucleosis

Chapter 13 Lesson 13. 2 anemia Hemolytic anemia sickle cell Hemochromatosis Hemophilia leukemia Mononucleosis Aplastic anemia Pernicious anemia thalassemia polycythemia vera purpura granulocytosis multiple myeloma Journal question: What is the term for white blood cells? How many types are there and what does each one do? Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 1

Objectives Describe various pathological conditions affecting blood. Copyright © 2011, 2008, 2005 by Saunders,

Objectives Describe various pathological conditions affecting blood. Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 2

Diseases of Red Blood Cells Anemia: Deficiency in erythrocytes or hemoglobin Other types of

Diseases of Red Blood Cells Anemia: Deficiency in erythrocytes or hemoglobin Other types of anemia: aplastic anemia Ø hemolytic anemia Ø pernicious anemia Ø sickle cell anemia Ø thalassemia Ø Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 3

Types of Anemia Aplastic anemia: failure of blood cell production due to aplasia or

Types of Anemia Aplastic anemia: failure of blood cell production due to aplasia or absence of cell formation of bone marrow cells Hemolytic anemia: reduction in red cells due to excessive destruction Pernicious anemia: lack of mature erythrocytes caused by inability to absorb vitamin B 12 into the body Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 4

Types of Anemia (cont’d) sickle cell: a hereditary disease characterized by abnormal shape of

Types of Anemia (cont’d) sickle cell: a hereditary disease characterized by abnormal shape of erythrocytes and by hemolysis thalassemia: an inherited defect in the ability to produce hemoglobin hemochromatosis: excess iron deposits throughout the body polycythemia vera: general increase in red blood cells Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 5

QUICK QUIZ: 3. What is the most common type of anemia? hemolytic anemia B.

QUICK QUIZ: 3. What is the most common type of anemia? hemolytic anemia B. sickle cell anemia C. iron deficiency anemia D. aplastic anemia A. Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 6

QUICK QUIZ: 3. What is the most common type of anemia? hemolytic anemia B.

QUICK QUIZ: 3. What is the most common type of anemia? hemolytic anemia B. sickle cell anemia C. iron deficiency anemia D. aplastic anemia A. Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 7

Types of Anemia Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier

Types of Anemia Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 8

Disorders of Blood Clotting hemophilia: Excessive bleeding caused by the lack of one of

Disorders of Blood Clotting hemophilia: Excessive bleeding caused by the lack of one of the protein substances necessary for blood clotting purpura: Multiple pinpoint hemorrhages and accumulation of blood under the skin Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 9

Diseases of White Blood Cells leukemia: An increase in cancerous white blood cells Ø

Diseases of White Blood Cells leukemia: An increase in cancerous white blood cells Ø acute myelogenous leukemia (AML) Ø acute lymphocytic leukemia (ALL) Ø chronic myelogenous leukemia (CML) Ø chronic lymphocytic leukemia (CLL) Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 10

Acute Leukemia Acute Myeloblastic Leukemia Acute Lymphoblastic Leukemia Copyright © 2011, 2008, 2005 by

Acute Leukemia Acute Myeloblastic Leukemia Acute Lymphoblastic Leukemia Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 11

Diseases of White Blood Cells granulocytosis: Abnormal increase in granulocytes in the blood mononucleosis:

Diseases of White Blood Cells granulocytosis: Abnormal increase in granulocytes in the blood mononucleosis: An infectious disease marked by increased numbers of leukocytes and enlarged cervical lymph nodes Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 12

Disease of Bone Marrow Cells multiple myeloma: Malignant neoplasm of bone marrow. Malignant cells

Disease of Bone Marrow Cells multiple myeloma: Malignant neoplasm of bone marrow. Malignant cells destroy bone tissue and cause overproduction of immunoglobulins. Copyright © 2011, 2008, 2005 by Saunders, an imprint of Elsevier Inc. All rights reserved. 13