Chapter 12 Respiratory System Oxygen Delivery A Cooperative

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Chapter 12 Respiratory System

Chapter 12 Respiratory System

Oxygen Delivery: A Cooperative Effort • Respiratory & cardiovascular system work together – Respiratory

Oxygen Delivery: A Cooperative Effort • Respiratory & cardiovascular system work together – Respiratory system: – Cardiovascular system:

Overview of the respiratory system

Overview of the respiratory system

Structure & Function of the Lungs • Lungs – Divided into several segments called:

Structure & Function of the Lungs • Lungs – Divided into several segments called: • Left lung has: • Right lung has: – These segments are made up of smaller units called:

Structure & Function of the Lungs • Consists of a system of tubes that

Structure & Function of the Lungs • Consists of a system of tubes that conduct air into and out of the lungs – Bronchi: – Bronchioles: – Terminal bronchioles: – Respiratory bronchioles: • Lead to alveolar ducts and sacs which contain multiple alveoli

The Lower Respiratory Tract Larynx Trachea Right bronchus Clusters of alveoli Left bronchus Bronchioles

The Lower Respiratory Tract Larynx Trachea Right bronchus Clusters of alveoli Left bronchus Bronchioles Figure 10. 3

Structure & Function of the Lungs • Alveoli: – Small air space bounded by

Structure & Function of the Lungs • Alveoli: – Small air space bounded by a thin epithelial wall called: – Alveoli are surrounded by pulmonary capillaries • These conditions promote: – Some cells is the septum produce a lipid material called: • This material

Structure & Function of the Lungs Fig. 12 -2 B

Structure & Function of the Lungs Fig. 12 -2 B

Respiration • Two functions of respiration: – Ventilation: – Includes: • Inspiration: • Expiration:

Respiration • Two functions of respiration: – Ventilation: – Includes: • Inspiration: • Expiration: – Gas Exchange: • Gases diffuse between blood, tissues, and pulmonary alveoli due to: Alveolar air ↑ P 02 105 mm. Hg ↓ PC 02 35 mm. Hg Blood (Pulmonary capillaries) P 02 20 mm. Hg PC 02 60 mm. Hg

Respiratory Cycle Figure 10. 9

Respiratory Cycle Figure 10. 9

Pleural Cavity • Pleura: • Pleural cavity: • Intrapleural pressure: – Normally less than

Pleural Cavity • Pleura: • Pleural cavity: • Intrapleural pressure: – Normally less than the pressure within the lungs (intrapulmonary pressure) • This holds the lungs: – Referred as “negative pressure” or subatmospheric because it is less than atmospheric pressure

Pneumothorax • Loss of negative intrapleural pressure which leads to: – Causes: • Lung

Pneumothorax • Loss of negative intrapleural pressure which leads to: – Causes: • Lung injury or pulmonary disease that allows: • Stab wound or penetrating injury to chest wall that permits: • Sometimes occurs without any apparent cause & is called: spontaneous pneumothorax – Occurs in: tall, white, males

Pneumothorax • Tension pneumothorax (A. K. A. sucking chest wound) – Development of: –

Pneumothorax • Tension pneumothorax (A. K. A. sucking chest wound) – Development of: – With inspiration intrapleural pressure: • Air flows: – With expiration intrapleural pressure: • Hole is plugged by tissue & air is: – Pressure builds up in pleural cavity causing:

Pneumothorax • Manifestations – Chest pain – Shortness of breath – Reduced breath sounds

Pneumothorax • Manifestations – Chest pain – Shortness of breath – Reduced breath sounds on affected side – Chest x-ray: lung collapse + air in pleural cavity

Pneumothorax • Treatment: – Chest tube inserted into pleural cavity; left in place until

Pneumothorax • Treatment: – Chest tube inserted into pleural cavity; left in place until tear in lung heals • Prevents: • Usually has a one way valve only allowing air to leave during expiration • Aids re-expansion of lung

Pneumothorax

Pneumothorax

Atelectasis • Collapse of all or part of a lung • Two types: –

Atelectasis • Collapse of all or part of a lung • Two types: – Obstructive atelectasis – Compression atelectasis

Atelectasis – Obstructive atelectasis: • Complete blockage of a bronchus by: • Air is

Atelectasis – Obstructive atelectasis: • Complete blockage of a bronchus by: • Air is absorbed from the blocked section of lung leading to: • If obstruction is relieved: • Can sometimes develop as a postoperative complication – Coughing and breathing are decreased – Mucous accumulates – To prevent this patients are encourage to breath deeply & cough

Atelectasis • Compression atelectasis: – Results when: – This prevents:

Atelectasis • Compression atelectasis: – Results when: – This prevents:

Pneumonia • Inflammation of the lung – Exudate spreads through the lung and fills

Pneumonia • Inflammation of the lung – Exudate spreads through the lung and fills the: – Affected portion of lung becomes relatively solid which is referred to as: – Can be classified in three ways: • Etiology • Anatomic distribution of inflammation • Predisposing factors

Pneumonia • Etiology: – Most important because: • Anatomic distribution of inflammation • Predisposing

Pneumonia • Etiology: – Most important because: • Anatomic distribution of inflammation • Predisposing factors

Pneumonia • Symptoms: • Treatment: – Bacterial: – Viral:

Pneumonia • Symptoms: • Treatment: – Bacterial: – Viral:

Pneumonia

Pneumonia

Tuberculosis • Special type of pneumonia caused by the bacterium: • Acquired by: –

Tuberculosis • Special type of pneumonia caused by the bacterium: • Acquired by: – Primary infection is walled off with a central region of necrotic cells which is called:

Tuberculosis • Infection usually stopped and granulomas heal with scarring • Symptoms usually caused:

Tuberculosis • Infection usually stopped and granulomas heal with scarring • Symptoms usually caused: • Infection can be reactivated: • Diagnosis – Skin test (Mantoux) – Chest x-ray – Sputum culture • Treatment: – With antibiotics & chemotherapeutic agents

Tuberculosis

Tuberculosis

Tuberculosis • Rare types of tuberculosis – Miliary tuberculosis: • Develops if tuberculous infection

Tuberculosis • Rare types of tuberculosis – Miliary tuberculosis: • Develops if tuberculous infection erodes into a large blood vessel: – Extra pulmonary tuberculosis: • Infection develops in other location of the body such as:

Bronchitis & Bronchiectasis • Acute bronchitis – Inflammation of lining of: – Commonly follows:

Bronchitis & Bronchiectasis • Acute bronchitis – Inflammation of lining of: – Commonly follows: • Chronic bronchitis – Results from: – Caused by: • Severe inflammation causing weakening & dilation of the bronchial wall is called: – Leads to:

Chronic Obstructive Lung Disease • Pulmonary disease caused primarily by chronic irritation due to

Chronic Obstructive Lung Disease • Pulmonary disease caused primarily by chronic irritation due to smoking • It is a combination of chronic bronchitis & emphysema – Emphysema • COPD is characterized by the following anatomic changes

Chronic Obstructive Lung Disease • Effects: – Individuals need to generate more pressure to

Chronic Obstructive Lung Disease • Effects: – Individuals need to generate more pressure to breath out:

Chronic Obstructive Lung Disease • COPD – Symptomatic treatment: • • • Bronchodilators Mucolytics

Chronic Obstructive Lung Disease • COPD – Symptomatic treatment: • • • Bronchodilators Mucolytics Cough suppressants Inhalers Avoidance of contact with people with URIs

Bronchial Asthma • Muscular spasms in the walls of: • Increased secretions by the:

Bronchial Asthma • Muscular spasms in the walls of: • Increased secretions by the: • Person may exibit: • Cause: – Usually: – Can be: • Treat with:

? ? QUESTIONS? ? 33

? ? QUESTIONS? ? 33