Chapter 10 Lymphatic System Diseases and Disorders Copyright

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Chapter 10 Lymphatic System Diseases and Disorders Copyright © 2010 Delmar, Cengage Learning. ALLALL

Chapter 10 Lymphatic System Diseases and Disorders Copyright © 2010 Delmar, Cengage Learning. ALLALL RIGHTS RESERVED.

Anatomy and Physiology • Lymph vessels, ducts, and nodes • Protects body from infection

Anatomy and Physiology • Lymph vessels, ducts, and nodes • Protects body from infection by filtering bacterial and nonbacterial products • Prevents waste products from entering circulatory system • Dependent on vascular system • Lymph is clear fluid Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Lymph and Blood Vessels Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Lymph and Blood Vessels Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Anatomy and Physiology • Two divisions of lymph system: – Right lymphatic duct drains

Anatomy and Physiology • Two divisions of lymph system: – Right lymphatic duct drains lymph from head, upper torso, and right arm – Left lymphatic duct • Also known as thoracic duct • Rest of body drains through this duct – Organs related to lymph system: • Tonsils, thymus gland, and spleen Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Animation Click Here to Play Lymphatic System Animation Copyright © 2010 Delmar, Cengage Learning.

Animation Click Here to Play Lymphatic System Animation Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Signs and Symptoms • Enlarged lymph glands or nodes, fever, fatigue, and weight

Common Signs and Symptoms • Enlarged lymph glands or nodes, fever, fatigue, and weight loss • Most diseases of lymphatic system related to diseases of other systems Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Signs and Symptoms • Lymphocytosis – Increased WBCs • Lymphocytopenia – Decreased WBCs

Common Signs and Symptoms • Lymphocytosis – Increased WBCs • Lymphocytopenia – Decreased WBCs Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Diagnostic Tests • Complete blood count (CBC) with differential • Lymphangiography – X-ray of

Diagnostic Tests • Complete blood count (CBC) with differential • Lymphangiography – X-ray of lymph system after dye injection • MRI • CAT scan • Biopsy of lymph nodes Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Lymphadenitis – Inflammation of lymph glands –

Common Diseases of the Lymphatic System • Lymphadenitis – Inflammation of lymph glands – Symptoms: • Swelling • Pain • Tenderness Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Lymphangitis – Swelling of lymph vessels due

Common Diseases of the Lymphatic System • Lymphangitis – Swelling of lymph vessels due to inflammation caused by strep infections following trauma – Characterized by red streak at bacterial entry extending to area of lymph node Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Lymphangitis – Other symptoms: • • Fever

Common Diseases of the Lymphatic System • Lymphangitis – Other symptoms: • • Fever Chills Malaise Cellulitis Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Lymphangitis – Treatment: • Antibiotics • Warm,

Common Diseases of the Lymphatic System • Lymphangitis – Treatment: • Antibiotics • Warm, moist packs • Elevation of affected area Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Lymphedema – Abnormal collection of lymph fluid

Common Diseases of the Lymphatic System • Lymphedema – Abnormal collection of lymph fluid in extremities – Possible causes: • • Surgery or radiation treatments Pregnancy Burns Trauma Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Lymphedema – Treatment: • Antibiotics • Compression

Common Diseases of the Lymphatic System • Lymphedema – Treatment: • Antibiotics • Compression therapy • Surgical intervention depending on cause Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Lymphedema Photo courtesy Mark L. Kuss Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS

Lymphedema Photo courtesy Mark L. Kuss Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Lymphoma – Neoplasms affecting lymphoid tissue –

Common Diseases of the Lymphatic System • Lymphoma – Neoplasms affecting lymphoid tissue – Affects normal lymphocyte production leading to impaired immunity – Most common type of blood cancer in United States Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Common Diseases of the Lymphatic System • Mononucleosis – Viral infection – Somewhat contagious

Common Diseases of the Lymphatic System • Mononucleosis – Viral infection – Somewhat contagious – Also known as kissing disease Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Rare Diseases • Kawasaki disease – Also known as mucocutaneous lymph node syndrome –

Rare Diseases • Kawasaki disease – Also known as mucocutaneous lymph node syndrome – Acute febrile disease – Found mostly in children Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Rare Diseases • Kawasaki disease – Symptoms: • • Rash similar to scarlet fever

Rare Diseases • Kawasaki disease – Symptoms: • • Rash similar to scarlet fever Edema of feet and hands Lethargy Congestion – Supportive treatment Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.

Effects of Aging • Decreased ability to produce antibodies – Thus, more prone to

Effects of Aging • Decreased ability to produce antibodies – Thus, more prone to infections • Increased susceptibility to autoimmune disorders • Impairment of vascular system also impacts function Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED.